GO:0098772	F	0.70	molecular function regulator
GO:0030234	F	0.68	enzyme regulator activity
GO:0005096	F	0.67	GTPase activator activity
GO:0003824	F	0.46	catalytic activity
GO:0097159	F	0.45	organic cyclic compound binding
GO:1901363	F	0.44	heterocyclic compound binding
GO:0036094	F	0.41	small molecule binding
GO:0046872	F	0.40	metal ion binding
GO:0016491	F	0.40	oxidoreductase activity
GO:0000166	F	0.40	nucleotide binding
GO:0016616	F	0.34	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050662	F	0.33	coenzyme binding
GO:0004448	F	0.33	isocitrate dehydrogenase activity
GO:0022857	F	0.23	transmembrane transporter activity
GO:0015075	F	0.22	ion transmembrane transporter activity
GO:0005216	F	0.21	ion channel activity
GO:0022836	F	0.20	gated channel activity
GO:0008324	F	0.20	cation transmembrane transporter activity
GO:0005261	F	0.19	cation channel activity
GO:0046873	F	0.18	metal ion transmembrane transporter activity
GO:0005244	F	0.18	voltage-gated ion channel activity
GO:0015077	F	0.17	monovalent inorganic cation transmembrane transporter activity
GO:0005248	F	0.14	voltage-gated sodium channel activity
GO:0019899	F	0.13	enzyme binding
