GO:0098772	F	0.56	molecular function regulator
GO:0005085	F	0.52	guanyl-nucleotide exchange factor activity
GO:0005089	F	0.48	Rho guanyl-nucleotide exchange factor activity
GO:0030676	F	0.28	Rac guanyl-nucleotide exchange factor activity
GO:0008092	F	0.28	cytoskeletal protein binding
GO:1901363	F	0.23	heterocyclic compound binding
GO:0097159	F	0.23	organic cyclic compound binding
GO:0003824	F	0.20	catalytic activity
GO:0046872	F	0.19	metal ion binding
GO:0019899	F	0.18	enzyme binding
GO:0097367	F	0.15	carbohydrate derivative binding
GO:0016787	F	0.15	hydrolase activity
GO:0003779	F	0.14	actin binding
GO:0031267	F	0.13	small GTPase binding
GO:0000166	F	0.13	nucleotide binding
GO:0035639	F	0.12	purine ribonucleoside triphosphate binding
GO:0032555	F	0.12	purine ribonucleotide binding
GO:0032550	F	0.12	purine ribonucleoside binding
GO:0016788	F	0.12	hydrolase activity, acting on ester bonds
GO:0005102	F	0.11	receptor binding
GO:0004872	F	0.11	receptor activity
