1hw8/1/1:D/1:C

Sequences

>1hw8-a1-m1-cD (length=372) [Search sequence]

HERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLD
EKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKA
WLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMISKGTEKA
LSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTTTEA
MIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPT
NEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVM
AGELSLMAALAA

>1hw8-a1-m1-cC (length=373) [Search sequence]

Structure information

PDB ID	1hw8 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH COMPACTIN (ALSO KNOWN AS MEVASTATIN)
Assembly ID	1
Resolution	2.1Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	405
Sequence identity between the two chains	1.0
PubMed citation	11349148

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	D	C
UniProt accession	P04035	P04035
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:1hw8D	BioLiP:1hw8C

3D structure

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Dimer structure: Chain 1 in red; Chain 2 in blue.

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Download:	1hw8-a1-m1-cD_1hw8-a1-m1-cC.pdb.gz

Full biological assembly

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Download:	1hw8-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures

1dq8/1/1:B/1:A 1dq8/1/1:C/1:D 1dq9/1/1:A/1:B 1dq9/1/1:C/1:D 1dqa/1/1:B/1:A 1dqa/1/1:D/1:C 1hw8/1/1:A/1:B 1hw9/1/1:B/1:A 1hw9/1/1:D/1:C 1hwi/1/1:A/1:B 1hwi/1/1:C/1:D 1hwj/1/1:B/1:A 1hwj/1/1:D/1:C 1hwk/1/1:B/1:A 1hwk/1/1:D/1:C 1hwl/1/1:B/1:A 1hwl/1/1:D/1:C 2q1l/1/1:A/1:B 2q1l/1/1:D/1:C 2q6b/1/1:B/1:A 2q6b/1/1:D/1:C 2q6c/1/1:B/1:A 2q6c/1/1:D/1:C 2r4f/1/1:B/1:A 2r4f/1/1:D/1:C 3bgl/1/1:A/1:B 3bgl/1/1:D/1:C 3cct/1/1:A/1:B 3cct/1/1:D/1:C 3ccw/1/1:A/1:B 3ccw/1/1:D/1:C 3ccz/1/1:B/1:A 3ccz/1/1:D/1:C 3cd0/1/1:A/1:B 3cd0/1/1:D/1:C 3cd5/1/1:A/1:B 3cd5/1/1:D/1:C 3cd7/1/1:A/1:B 3cd7/1/1:D/1:C 3cda/1/1:B/1:A 3cda/1/1:D/1:C 3cdb/1/1:A/1:B 3cdb/1/1:D/1:C

Other dimers with similar sequences but different poses

1hwi/1/1:D/1:B 1dq8/1/1:B/1:D 1dq8/1/1:C/1:A 1dq9/1/1:A/1:C 1dq9/1/1:B/1:D 1dqa/1/1:C/1:A 1dqa/1/1:D/1:B 1hw8/1/1:C/1:A 1hw8/1/1:D/1:B 1hw9/1/1:C/1:A 1hw9/1/1:D/1:B 1hwi/1/1:C/1:A 1hwj/1/1:C/1:A 1hwj/1/1:D/1:B 1hwk/1/1:C/1:A 1hwk/1/1:D/1:B 1hwl/1/1:C/1:A 1hwl/1/1:D/1:B 2q1l/1/1:A/1:C 2q1l/1/1:D/1:B 2q6b/1/1:C/1:A 2q6b/1/1:D/1:B 2q6c/1/1:C/1:A 2q6c/1/1:D/1:B 2r4f/1/1:C/1:A 2r4f/1/1:D/1:B 3bgl/1/1:C/1:A 3bgl/1/1:D/1:B 3cct/1/1:C/1:A 3cct/1/1:D/1:B 3ccw/1/1:C/1:A 3ccw/1/1:D/1:B 3ccz/1/1:C/1:A 3ccz/1/1:D/1:B 3cd0/1/1:C/1:A 3cd0/1/1:D/1:B 3cd5/1/1:C/1:A 3cd5/1/1:D/1:B 3cd7/1/1:A/1:C 3cd7/1/1:D/1:B 3cda/1/1:C/1:A 3cda/1/1:D/1:B 3cdb/1/1:C/1:A 3cdb/1/1:D/1:B

2q6c/1/1:C/1:B 1dq8/1/1:C/1:B 1dq8/1/1:D/1:A 1dq9/1/1:A/1:D 1dq9/1/1:B/1:C 1dqa/1/1:C/1:B 1dqa/1/1:D/1:A 1hw8/1/1:C/1:B 1hw8/1/1:D/1:A 1hw9/1/1:C/1:B 1hw9/1/1:D/1:A 1hwi/1/1:C/1:B 1hwi/1/1:D/1:A 1hwj/1/1:B/1:C 1hwj/1/1:D/1:A 1hwk/1/1:B/1:C 1hwk/1/1:D/1:A 1hwl/1/1:B/1:C 1hwl/1/1:D/1:A 2q1l/1/1:A/1:D 2q1l/1/1:B/1:C 2q6b/1/1:C/1:B 2q6b/1/1:D/1:A 2q6c/1/1:D/1:A 2r4f/1/1:C/1:B 2r4f/1/1:D/1:A 3bgl/1/1:C/1:B 3bgl/1/1:D/1:A 3cct/1/1:C/1:B 3cct/1/1:D/1:A 3ccw/1/1:C/1:B 3ccw/1/1:D/1:A 3ccz/1/1:C/1:B 3ccz/1/1:D/1:A 3cd0/1/1:C/1:B 3cd0/1/1:D/1:A 3cd5/1/1:C/1:B 3cd5/1/1:D/1:A 3cd7/1/1:A/1:D 3cd7/1/1:B/1:C 3cda/1/1:C/1:B 3cda/1/1:D/1:A 3cdb/1/1:C/1:B 3cdb/1/1:D/1:A