1iss/1/1:A/1:B

Sequences

>1iss-a1-m1-cA (length=452) [Search sequence]

RSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVL
LPNITLGSEIRDSCWHSSVALEQSIEFIRDSLIKPIAGVIGPGSSSVAIQVQNLLQLFDI
PQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESG
MDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLL
SAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLD
TNTRNPWFPEFWQHRFQCRLPGHLLENPNFKKVCTGNESLEENYVQDSKMGFVINAIYAM
AHGLQNMHHALCPGHVGLCDAMKPIDGRKLLDFLIKSSFVGVSGEEVWFDEKGDAPGRYD
IMNLQYTEANRYDYVHVGTWHEGVLNIDDYKI

>1iss-a1-m1-cB (length=452) [Search sequence]

Structure information

PDB ID	1iss (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with an antagonist
Assembly ID	1
Resolution	3.3Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	23
Sequence identity between the two chains	1.0
PubMed citation	11867751

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	A	B
UniProt accession	P23385	P23385
Species	10116 (Rattus norvegicus)	10116 (Rattus norvegicus)
Function annotation	BioLiP:1issA	BioLiP:1issB

3D structure

Switch viewer: [NGL] [JSmol]

Dimer structure: Chain 1 in red; Chain 2 in blue.

Download:

1iss-a1-m1-cA_1iss-a1-m1-cB.pdb.gz

Full biological assembly

Download:

1iss-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures	1ewt/1/1:A/1:B 7dgd/1/1:A/1:B
Other dimers with similar sequences but different poses	1ewk/1/1:A/1:B 1ewv/1/1:A/1:B 1isr/1/1:A/2:A 3ks9/1/1:B/1:A 7dge/1/1:A/1:B