1pw6/4/1:A/4:B

Sequences
>1pw6-a4-m1-cA (length=121) [Search sequence]
STKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKP
LEEVLNLAQRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIIST
L
>1pw6-a4-m4-cB (length=129) [Search sequence]
SSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELK
PLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITF
CQSIISTLT
Structure information
PDB ID 1pw6 (database links: RCSB PDB PDBe PDBj PDBsum)
Title Low Micromolar Small Molecule Inhibitor of IL-2
Assembly ID 4
Resolution 2.6Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 25
Sequence identity between the two chains 1.0
PubMed citation 14664558
Chain information
Chain 1 Chain 2
Model ID 1 4
Chain ID A B
UniProt accession P60568 P60568
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:1pw6A BioLiP:1pw6B
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 1pw6-a4-m1-cA_1pw6-a4-m4-cB.pdb.gz
Full biological assembly
Download: 1pw6-assembly4.cif.gz
Similar dimers
Other dimers with similar sequences and structures 1pw6/3/1:A/4:B 1pw6/3/2:A/3:B
Other dimers with similar sequences but different poses
  • 1pw6/3/2:A/4:B 1pw6/3/1:A/3:B
  • 1qvn/4/4:C/1:A 1qvn/2/1:B/1:D 1qvn/3/1:B/1:D 1qvn/3/3:C/2:A
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