2aaz/8/1:O/1:P

Sequences

>2aaz-a8-m1-cO (length=299) [Search sequence]

PDHEEYQYLDLIRRIINVGEVRPDRTGTGTVALFAPPSFRFSLADNTLPLLTTKRVFLRG VIAELLWFVSGCTDAKMLSSQGVGIWDGNGSKEFLEKVGLGHRREGDLGPVYGFQWRHFG AEYTDADGDYKGKGVDQLQRVIDTIKNNPTDRRIILSAWNPKDLPLMALPPCHMFCQFFV SLPPPGSKPKLSCLMYQRSCDLGLGVPFNIASYALLTHMIALITDTEPHEFILQMGDAHV YRDHVEPLKTQLEREPRDFPKLKWARSKEEIGDIDGFKVEDFVVEGYKPWGKIDMKMSA

>2aaz-a8-m1-cP (length=299) [Search sequence]

PDHEEYQYLDLIRRIINVGEVRPDRTGTGTVALFAPPSFRFSLADNTLPLLTTKRVFLRG VIAELLWFVSGCTDAKMLSSQGVGIWDGNGSKEFLEKVGLGHRREGDLGPVYGFQWRHFG AEYTDADGDYKGKGVDQLQRVIDTIKNNPTDRRIILSAWNPKDLPLMALPPCHMFCQFFV SLPPPGSKPKLSCLMYQRSCDLGLGVPFNIASYALLTHMIALITDTEPHEFILQMGDAHV YRDHVEPLKTQLEREPRDFPKLKWARSKEEIGDIDGFKVEDFVVEGYKPWGKIDMKMSA

Structure information

PDB ID	2aaz (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Cryptococcus neoformans thymidylate synthase complexed with substrate and an antifolate
Assembly ID	8
Resolution	2.08Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	112
Sequence identity between the two chains	1.0
PubMed citation	16204883

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	O	P
UniProt accession	P0CS12	P0CS12
Species	5207 (Cryptococcus neoformans)	5207 (Cryptococcus neoformans)
Function annotation	BioLiP:2aazO	BioLiP:2aazP

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 2aaz-a8-m1-cO_2aaz-a8-m1-cP.pdb.gz

Full biological assembly Download: 2aaz-assembly8.cif.gz

Similar dimers

Other dimers with similar sequences and structures

2aaz/1/1:A/1:B 2aaz/2/1:C/1:D 2aaz/3/1:E/1:F 2aaz/4/1:G/1:H 2aaz/5/1:I/1:J 2aaz/6/1:K/1:L 2aaz/7/1:M/1:N