2b4s/1/1:B/1:D

Sequences
>2b4s-a1-m1-cB (length=294) [Search sequence]
DEWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLN
EASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTL
QEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIETDRKGGKG
LLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLD
QPDNCPERVTDLMRMCWQFNPNMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENK
>2b4s-a1-m1-cD (length=294) [Search sequence]
DEWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLN
EASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTL
QEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIETDRKGGKG
LLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLD
QPDNCPERVTDLMRMCWQFNPNMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENK
Structure information
PDB ID 2b4s (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal structure of a complex between PTP1B and the insulin receptor tyrosine kinase
Assembly ID 1
Resolution 2.3Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 59
Sequence identity between the two chains 1.0
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID B D
UniProt accession P06213 P06213
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 2b4s-a1-m1-cB_2b4s-a1-m1-cD.pdb.gz
Full biological assembly
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Download: 2b4s-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 1ir3/1/1:A/2:A 1gag/2/1:A/2:A 4xlv/1/1:A/2:A
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