2fsz/2/1:A/4:B

Sequences
>2fsz-a2-m1-cA (length=223) [Search sequence]
SPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELS
LFDQVRLLESSWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKSVEGILEIFDMLLAT
TSRFRELKLQHKEYLCVKAMILLNSSMSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRL
ANLLMLLSHVRHASNKGMEHLLNMNVVPVYDLLLEMLNAHVLR
>2fsz-a2-m4-cB (length=227) [Search sequence]
LDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGF
VELSLFDQVRLLESSWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKSVEGILEIFDM
LLATTSRFRELKLQHKEYLCVKAMILLNSSMSRKLAHLLNAVTDALVWVIAKSGISSQQQ
SMRLANLLMLLSHVRHASNKGMEHLLNMNVVPVYDLLLEMLNAHVLR
Structure information
PDB ID 2fsz (database links: RCSB PDB PDBe PDBj PDBsum)
Title A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor beta
Assembly ID 2
Resolution 2.2Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 49
Sequence identity between the two chains 1.0
PubMed citation 16782818
Chain information
Chain 1 Chain 2
Model ID 1 4
Chain ID A B
UniProt accession Q92731 Q92731
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:2fszA BioLiP:2fszB
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 2fsz-a2-m1-cA_2fsz-a2-m4-cB.pdb.gz
Full biological assembly
Download: 2fsz-assembly2.cif.gz
Similar dimers
Other dimers with similar sequences and structures 2fsz/2/2:A/3:B 2fsz/2/3:A/1:B 2fsz/2/4:A/2:B
Other dimers with similar sequences but different poses
  • 2nv7/1/1:B/1:A 1hj1/1/1:A/2:A 1nde/2/1:A/2:A 1qkm/1/1:A/2:A 1qkn/1/1:A/2:A 1u3q/1/1:A/1:C 1u3q/2/1:D/1:B 1u3r/1/1:B/1:A 1u3s/1/1:B/1:A 1u9e/3/1:A/1:B 1x76/1/1:A/1:B 1x78/1/1:A/1:B 1x7b/1/1:B/1:A 1x7j/1/1:A/1:B 1yy4/1/1:A/1:B 1yye/1/1:B/1:A 1zaf/1/1:A/1:B 2fsz/1/1:A/1:B 2fsz/2/1:A/1:B 2fsz/2/2:A/2:B 2fsz/2/3:A/3:B 2fsz/2/4:A/4:B 2i0g/1/1:A/1:B 2jj3/1/1:A/1:B 2qtu/1/1:A/1:B 2yjd/1/1:A/1:B 2yly/1/1:A/1:B 2z4b/1/1:A/1:B 3oll/3/1:B/1:A 3ols/3/1:B/1:A 3omo/3/1:B/1:A 3omp/3/1:B/1:A 3omq/3/1:B/1:A 4zi1/1/1:A/2:A 5toa/1/1:A/1:B 7xvy/1/1:A/1:B 7xvz/1/1:A/1:B 7xwp/1/1:A/1:B 7xwq/1/1:A/1:B 7xwr/1/1:A/1:B
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