2g24/3/2:A/3:B

Sequences
>2g24-a3-m2-cA (length=329) [Search sequence]
SSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDAS
DSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGV
VGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSELGGQIVLGGSDPQHYEGNFH
YINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKR
LFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGP
TWALGATFIRKFYTEFDRRNNRIGFALAR
>2g24-a3-m3-cB (length=329) [Search sequence]
SSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDAS
DSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGV
VGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSELGGQIVLGGSDPQHYEGNFH
YINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKR
LFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGP
TWALGATFIRKFYTEFDRRNNRIGFALAR
Structure information
PDB ID 2g24 (database links: RCSB PDB PDBe PDBj PDBsum)
Title Ketopiperazine-Based Renin Inhibitors: Optimization of the ""C"" Ring
Assembly ID 3
Resolution 1.9Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 14
Sequence identity between the two chains 1.0
PubMed citation 16480874
Chain information
Chain 1 Chain 2
Model ID 2 3
Chain ID A B
UniProt accession P00797 P00797
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:2g24A
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 2g24-a3-m2-cA_2g24-a3-m3-cB.pdb.gz
Full biological assembly
Download: 2g24-assembly3.cif.gz
Similar dimers
Other dimers with similar sequences and structures 2fs4/3/1:A/3:B 2fs4/3/1:B/2:A 2fs4/3/2:B/3:A 2g1o/3/1:A/3:B 2g1o/3/1:B/2:A 2g1o/3/2:B/3:A 2g1r/3/1:A/3:B 2g1r/3/1:B/2:A 2g1r/3/2:B/3:A 2g1y/3/1:A/2:B 2g1y/3/1:B/3:A 2g1y/3/2:A/3:B 2g20/3/1:A/2:B 2g20/3/1:B/3:A 2g20/3/2:A/3:B 2g24/3/1:A/2:B 2g24/3/1:B/3:A 2g26/3/1:A/3:B 2g26/3/1:B/2:A 2g26/3/2:B/3:A 2iko/1/1:B/2:A 2iko/1/2:B/3:A 2iko/1/3:B/1:A 2iku/1/1:A/3:B 2iku/1/1:B/2:A 2iku/1/2:B/3:A 2il2/1/1:A/2:B 2il2/1/1:B/3:A 2il2/1/2:A/3:B 3own/5/1:A/3:B 3own/5/1:B/2:A 3own/5/2:B/3:A 3vsw/3/1:A/3:B 3vsw/3/1:B/2:A 3vsw/3/2:B/3:A 3vsx/3/1:A/2:B 3vsx/3/1:B/3:A 3vsx/3/2:A/3:B 3vuc/3/1:B/2:A 3vuc/3/2:B/3:A 3vuc/3/3:B/1:A 3vyd/3/1:A/3:B 3vyd/3/1:B/2:A 3vyd/3/2:B/3:A 3vye/3/1:A/3:B 3vye/3/1:B/2:A 3vye/3/2:B/3:A 3vyf/3/1:B/2:A 3vyf/3/2:B/3:A 3vyf/3/3:B/1:A 4s1g/3/1:B/2:A 4s1g/3/2:B/3:A 4s1g/3/3:B/1:A 4xx3/3/1:B/2:A 4xx3/3/2:B/3:A 4xx3/3/3:B/1:A 4xx4/3/1:B/2:A 4xx4/3/2:B/3:A 4xx4/3/3:B/1:A 5koq/3/1:B/3:A 5koq/3/2:B/1:A 5koq/3/3:B/2:A 5kos/3/1:A/2:B 5kos/3/2:A/3:B 5kos/3/3:A/1:B 5kot/3/1:A/3:B 5kot/3/2:A/1:B 5kot/3/3:A/2:B 5sxn/3/1:A/2:B 5sxn/3/1:B/3:A 5sxn/3/2:A/3:B 5sy2/3/1:B/2:A 5sy2/3/2:B/3:A 5sy2/3/3:B/1:A 5sz9/3/1:B/2:A 5sz9/3/2:B/3:A 5sz9/3/3:B/1:A 5t4s/3/1:B/2:A 5t4s/3/2:B/3:A 5t4s/3/3:B/1:A 5tmg/3/1:A/2:B 5tmg/3/1:B/3:A 5tmg/3/2:A/3:B 5tmk/3/1:B/3:A 5tmk/3/2:B/1:A 5tmk/3/3:B/2:A
Other dimers with similar sequences but different poses
  • 3sfc/5/2:A/3:A 1bbs/3/1:A/2:A 1bbs/3/3:A/1:A 1bbs/3/3:A/2:A 1bbs/4/1:A/2:A 1bbs/4/3:A/1:A 1bbs/4/3:A/2:A 2fs4/3/1:A/2:A 2fs4/3/1:A/3:A 2fs4/3/2:A/3:A 2fs4/5/1:A/2:A 2fs4/5/1:A/3:A 2fs4/5/2:A/3:A 2g1o/3/1:A/2:A 2g1o/3/1:A/3:A 2g1o/3/2:A/3:A 2g1o/5/1:A/2:A 2g1o/5/1:A/3:A 2g1o/5/2:A/3:A 2g1r/3/1:A/2:A 2g1r/3/1:A/3:A 2g1r/3/2:A/3:A 2g1y/3/1:A/2:A 2g1y/3/1:A/3:A 2g1y/3/2:A/3:A 2g1y/5/1:A/2:A 2g1y/5/1:A/3:A 2g1y/5/2:A/3:A 2g20/3/1:A/2:A 2g20/3/1:A/3:A 2g20/3/2:A/3:A 2g24/3/1:A/2:A 2g24/3/1:A/3:A 2g24/3/2:A/3:A 2g26/3/1:A/2:A 2g26/3/1:A/3:A 2g26/3/2:A/3:A 2iko/1/1:A/2:A 2iko/1/1:A/3:A 2iko/1/2:A/3:A 2iku/1/1:A/2:A 2iku/1/1:A/3:A 2iku/1/2:A/3:A 2il2/1/1:A/2:A 2il2/1/1:A/3:A 2il2/1/2:A/3:A 2v16/1/1:C/2:C 2v16/1/1:C/3:C 2v16/1/2:C/3:C 3own/3/1:A/2:A 3own/3/1:A/3:A 3own/3/2:A/3:A 3own/5/1:A/2:A 3own/5/1:A/3:A 3own/5/2:A/3:A 3sfc/3/1:A/2:A 3sfc/3/1:A/3:A 3sfc/3/2:A/3:A 3sfc/4/1:A/2:A 3sfc/4/1:A/3:A 3sfc/4/2:A/3:A 3sfc/5/1:A/2:A 3sfc/5/1:A/3:A 3vsw/3/1:A/2:A 3vsw/3/1:A/3:A 3vsw/3/2:A/3:A 3vsw/4/1:A/2:A 3vsw/4/1:A/3:A 3vsw/4/2:A/3:A 3vsx/3/1:A/2:A 3vsx/3/1:A/3:A 3vsx/3/2:A/3:A 3vuc/3/1:A/2:A 3vuc/3/1:A/3:A 3vuc/3/2:A/3:A 3vyd/3/1:A/2:A 3vyd/3/1:A/3:A 3vyd/3/2:A/3:A 3vye/3/1:A/2:A 3vye/3/1:A/3:A 3vye/3/2:A/3:A 3vyf/3/1:A/2:A 3vyf/3/1:A/3:A 3vyf/3/2:A/3:A 4q1n/3/1:A/2:A 4q1n/3/1:A/3:A 4q1n/3/2:A/3:A 4ryc/3/1:A/2:A 4ryc/3/1:A/3:A 4ryc/3/2:A/3:A 4ryg/3/1:A/2:A 4ryg/3/1:A/3:A 4ryg/3/2:A/3:A 4rz1/3/1:A/2:A 4rz1/3/1:A/3:A 4rz1/3/2:A/3:A 4s1g/3/1:A/2:A 4s1g/3/1:A/3:A 4s1g/3/2:A/3:A 4xx3/3/1:A/2:A 4xx3/3/1:A/3:A 4xx3/3/2:A/3:A 4xx3/4/1:A/2:A 4xx3/4/1:A/3:A 4xx3/4/2:A/3:A 4xx4/3/1:A/2:A 4xx4/3/1:A/3:A 4xx4/3/2:A/3:A 4xx4/4/1:A/2:A 4xx4/4/1:A/3:A 4xx4/4/2:A/3:A 5koq/3/1:A/2:A 5koq/3/1:A/3:A 5koq/3/2:A/3:A 5kos/3/1:A/2:A 5kos/3/1:A/3:A 5kos/3/2:A/3:A 5kot/3/1:A/2:A 5kot/3/1:A/3:A 5kot/3/2:A/3:A 5sxn/3/1:A/2:A 5sxn/3/1:A/3:A 5sxn/3/2:A/3:A 5sy2/3/1:A/2:A 5sy2/3/1:A/3:A 5sy2/3/2:A/3:A 5sz9/3/1:A/2:A 5sz9/3/1:A/3:A 5sz9/3/2:A/3:A 5t4s/3/1:A/2:A 5t4s/3/1:A/3:A 5t4s/3/2:A/3:A 5tmg/3/1:A/2:A 5tmg/3/1:A/3:A 5tmg/3/2:A/3:A 5tmk/3/1:A/2:A 5tmk/3/1:A/3:A 5tmk/3/2:A/3:A
  • 3sfc/5/3:B/3:A 1bbs/3/1:A/2:B 1bbs/3/3:A/1:B 1bbs/3/3:B/2:A 1bil/1/1:B/1:A 1bim/1/1:B/1:A 1hrn/1/1:B/1:A 2fs4/3/1:A/2:B 2fs4/3/1:B/3:A 2fs4/3/2:A/3:B 2g1o/3/1:A/2:B 2g1o/3/1:B/3:A 2g1o/3/2:A/3:B 2g1r/3/1:A/2:B 2g1r/3/1:B/3:A 2g1r/3/2:A/3:B 2g1y/3/1:A/3:B 2g1y/3/1:B/2:A 2g1y/3/2:B/3:A 2g20/3/1:A/3:B 2g20/3/1:B/2:A 2g20/3/2:B/3:A 2g24/3/1:A/3:B 2g24/3/1:B/2:A 2g24/3/2:B/3:A 2g26/3/1:A/2:B 2g26/3/1:B/3:A 2g26/3/2:A/3:B 2i4q/1/1:A/1:B 2iko/1/1:B/1:A 2iko/1/2:B/2:A 2iko/1/3:B/3:A 2iku/1/1:A/1:B 2iku/1/2:A/2:B 2iku/1/3:A/3:B 2il2/1/1:A/1:B 2il2/1/2:A/2:B 2il2/1/3:A/3:B 2v12/1/1:O/1:C 2v12/2/1:O/1:C 2v16/1/1:O/1:C 2v16/1/2:O/2:C 2v16/1/3:O/3:C 3own/5/1:A/1:B 3own/5/2:A/2:B 3own/5/3:A/3:B 3sfc/3/1:A/1:B 3sfc/3/2:A/2:B 3sfc/3/3:B/3:A 3sfc/4/1:A/1:B 3sfc/4/2:A/2:B 3sfc/4/3:B/3:A 3sfc/5/1:A/1:B 3sfc/5/2:A/2:B 3vsw/3/1:A/1:B 3vsw/3/2:A/2:B 3vsw/3/3:A/3:B 3vsx/3/1:A/1:B 3vsx/3/2:A/2:B 3vsx/3/3:A/3:B 3vuc/3/1:B/1:A 3vuc/3/2:B/2:A 3vuc/3/3:B/3:A 3vyd/3/1:A/1:B 3vyd/3/2:A/2:B 3vyd/3/3:A/3:B 3vye/3/1:A/1:B 3vye/3/2:A/2:B 3vye/3/3:A/3:B 3vyf/3/1:B/1:A 3vyf/3/2:B/2:A 3vyf/3/3:B/3:A 4q1n/3/1:A/1:B 4q1n/3/2:A/2:B 4q1n/3/3:B/3:A 4ryc/3/1:A/1:B 4ryc/3/2:A/2:B 4ryc/3/3:B/3:A 4ryg/3/1:A/1:B 4ryg/3/2:A/2:B 4ryg/3/3:B/3:A 4rz1/3/1:A/1:B 4rz1/3/2:A/2:B 4rz1/3/3:B/3:A 4s1g/3/1:B/1:A 4s1g/3/2:B/2:A 4s1g/3/3:B/3:A 4xx3/3/1:B/1:A 4xx3/3/2:B/2:A 4xx3/3/3:B/3:A 4xx4/3/1:B/1:A 4xx4/3/2:B/2:A 4xx4/3/3:B/3:A 5koq/3/1:B/1:A 5koq/3/2:B/2:A 5koq/3/3:B/3:A 5kos/3/1:A/1:B 5kos/3/2:A/2:B 5kos/3/3:A/3:B 5kot/3/1:A/1:B 5kot/3/2:A/2:B 5kot/3/3:A/3:B 5sxn/3/1:A/1:B 5sxn/3/2:A/2:B 5sxn/3/3:A/3:B 5sy2/3/1:B/1:A 5sy2/3/2:B/2:A 5sy2/3/3:B/3:A 5sz9/3/1:B/1:A 5sz9/3/2:B/2:A 5sz9/3/3:B/3:A 5t4s/3/1:B/1:A 5t4s/3/2:B/2:A 5t4s/3/3:B/3:A 5tmg/3/1:A/1:B 5tmg/3/2:A/2:B 5tmg/3/3:A/3:B 5tmk/3/1:B/1:A 5tmk/3/2:B/2:A 5tmk/3/3:B/3:A
  • 3sfc/5/3:B/2:B 1bbs/3/1:B/2:B 1bbs/3/3:B/1:B 1bbs/3/3:B/2:B 2fs4/3/1:B/2:B 2fs4/3/1:B/3:B 2fs4/3/2:B/3:B 2fs4/4/1:B/2:B 2fs4/4/1:B/3:B 2fs4/4/2:B/3:B 2g1o/3/1:B/2:B 2g1o/3/1:B/3:B 2g1o/3/2:B/3:B 2g1o/4/1:B/2:B 2g1o/4/1:B/3:B 2g1o/4/2:B/3:B 2g1r/3/1:B/2:B 2g1r/3/1:B/3:B 2g1r/3/2:B/3:B 2g1y/3/1:B/2:B 2g1y/3/1:B/3:B 2g1y/3/2:B/3:B 2g1y/4/1:B/2:B 2g1y/4/1:B/3:B 2g1y/4/2:B/3:B 2g20/3/1:B/2:B 2g20/3/1:B/3:B 2g20/3/2:B/3:B 2g22/3/1:B/2:B 2g22/3/1:B/3:B 2g22/3/2:B/3:B 2g24/3/1:B/2:B 2g24/3/1:B/3:B 2g24/3/2:B/3:B 2g24/4/1:B/2:B 2g24/4/1:B/3:B 2g24/4/2:B/3:B 2g26/3/1:B/2:B 2g26/3/1:B/3:B 2g26/3/2:B/3:B 2g26/4/1:B/2:B 2g26/4/1:B/3:B 2g26/4/2:B/3:B 2g27/3/1:B/2:B 2g27/3/1:B/3:B 2g27/3/2:B/3:B 2iko/1/1:B/2:B 2iko/1/1:B/3:B 2iko/1/2:B/3:B 2iku/1/1:B/2:B 2iku/1/1:B/3:B 2iku/1/2:B/3:B 2il2/1/1:B/2:B 2il2/1/1:B/3:B 2il2/1/2:B/3:B 2v16/1/1:O/2:O 2v16/1/3:O/1:O 2v16/1/3:O/2:O 3own/4/1:B/2:B 3own/4/1:B/3:B 3own/4/2:B/3:B 3own/5/1:B/2:B 3own/5/1:B/3:B 3own/5/2:B/3:B 3sfc/3/1:B/2:B 3sfc/3/3:B/1:B 3sfc/3/3:B/2:B 3sfc/4/1:B/2:B 3sfc/4/3:B/1:B 3sfc/4/3:B/2:B 3sfc/5/1:B/2:B 3sfc/5/3:B/1:B 3vsw/3/1:B/2:B 3vsw/3/1:B/3:B 3vsw/3/2:B/3:B 3vsw/5/1:B/2:B 3vsw/5/1:B/3:B 3vsw/5/2:B/3:B 3vsx/3/1:B/2:B 3vsx/3/1:B/3:B 3vsx/3/2:B/3:B 3vuc/3/1:B/2:B 3vuc/3/1:B/3:B 3vuc/3/2:B/3:B 3vyd/3/1:B/2:B 3vyd/3/1:B/3:B 3vyd/3/2:B/3:B 3vye/3/1:B/2:B 3vye/3/1:B/3:B 3vye/3/2:B/3:B 3vyf/3/1:B/2:B 3vyf/3/1:B/3:B 3vyf/3/2:B/3:B 4q1n/3/1:B/2:B 4q1n/3/3:B/1:B 4q1n/3/3:B/2:B 4ryc/3/1:B/2:B 4ryc/3/3:B/1:B 4ryc/3/3:B/2:B 4ryg/3/1:B/2:B 4ryg/3/3:B/1:B 4ryg/3/3:B/2:B 4rz1/3/1:B/2:B 4rz1/3/3:B/1:B 4rz1/3/3:B/2:B 4s1g/3/1:B/2:B 4s1g/3/1:B/3:B 4s1g/3/2:B/3:B 4xx3/3/1:B/2:B 4xx3/3/1:B/3:B 4xx3/3/2:B/3:B 4xx3/5/1:B/2:B 4xx3/5/1:B/3:B 4xx3/5/2:B/3:B 4xx4/3/1:B/2:B 4xx4/3/1:B/3:B 4xx4/3/2:B/3:B 4xx4/5/1:B/2:B 4xx4/5/1:B/3:B 4xx4/5/2:B/3:B 5koq/3/1:B/2:B 5koq/3/1:B/3:B 5koq/3/2:B/3:B 5kos/3/1:B/2:B 5kos/3/1:B/3:B 5kos/3/2:B/3:B 5kot/3/1:B/2:B 5kot/3/1:B/3:B 5kot/3/2:B/3:B 5sxn/3/1:B/2:B 5sxn/3/1:B/3:B 5sxn/3/2:B/3:B 5sy2/3/1:B/2:B 5sy2/3/1:B/3:B 5sy2/3/2:B/3:B 5sy3/3/1:A/2:A 5sy3/3/1:A/3:A 5sy3/3/2:A/3:A 5sz9/3/1:B/2:B 5sz9/3/1:B/3:B 5sz9/3/2:B/3:B 5t4s/3/1:B/2:B 5t4s/3/1:B/3:B 5t4s/3/2:B/3:B 5tmg/3/1:B/2:B 5tmg/3/1:B/3:B 5tmg/3/2:B/3:B 5tmk/3/1:B/2:B 5tmk/3/1:B/3:B 5tmk/3/2:B/3:B
  • 3km4/1/1:B/1:A 1rne/1/2:A/1:A 5vrp/3/1:A/1:B
  • 3g72/3/1:A/1:B 3d91/3/1:A/1:B 3g6z/3/1:B/1:A 3g70/3/1:A/2:B 3k1w/3/1:A/1:B
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