2h42/4/1:C/2:C

Sequences
>2h42-a4-m1-cC (length=317) [Search sequence]
EETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEV
LCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHD
LDHRGVNNSYIQRCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILAT
DLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVA
TEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLL
DGCRKNRQKWQALAEQQ
>2h42-a4-m2-cC (length=317) [Search sequence]
EETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEV
LCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHD
LDHRGVNNSYIQRCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILAT
DLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVA
TEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLL
DGCRKNRQKWQALAEQQ
Structure information
PDB ID 2h42 (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal structure of PDE5 in complex with sildenafil
Assembly ID 4
Resolution 2.3Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 43
Sequence identity between the two chains 1.0
PubMed citation 16735511
Chain information
Chain 1 Chain 2
Model ID 1 2
Chain ID C C
UniProt accession O76074 O76074
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:2h42C BioLiP:2h42C
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 2h42-a4-m1-cC_2h42-a4-m2-cC.pdb.gz
Full biological assembly
Download: 2h42-assembly4.cif.gz

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