2ivv/1/1:A/2:A

Sequences
>2ivv-a1-m1-cA (length=282) [Search sequence]
GPLSLSVDAFKIKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKEN
ASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRLTM
GDLISFAWQISQGMQYLAEMSLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSVKRS
QGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHR
MERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVK
>2ivv-a1-m2-cA (length=282) [Search sequence]
GPLSLSVDAFKIKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKEN
ASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRLTM
GDLISFAWQISQGMQYLAEMSLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSVKRS
QGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHR
MERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVK
Structure information
PDB ID 2ivv (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal structure of phosphorylated RET tyrosine kinase domain complexed with the inhibitor PP1
Assembly ID 1
Resolution 2.25Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 108
Sequence identity between the two chains 1.0
PubMed citation 16928683
Chain information
Chain 1 Chain 2
Model ID 1 2
Chain ID A A
UniProt accession P07949 P07949
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:2ivvA BioLiP:2ivvA
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 2ivv-a1-m1-cA_2ivv-a1-m2-cA.pdb.gz
Full biological assembly
Download: 2ivv-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences and structures 2ivt/1/1:A/2:A 2ivu/1/1:A/2:A 2x2k/1/1:A/2:A 2x2l/1/1:A/2:A 2x2m/1/1:B/1:A 4cki/1/1:A/2:A 4ckj/1/1:A/2:A 5amn/1/1:A/2:A 5fm2/1/1:A/2:A 5fm3/1/1:A/2:A 6i83/1/1:A/2:A 7nzn/1/1:A/2:A

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