2vwi/1/1:A/1:C

Sequences

>2vwi-a1-m1-cA (length=236) [Search sequence]

NRDDYELQEVIGTAVVQAAYCEKVAIKRINAMSQCHHPNIVSYYTSFVVKDELWLVMKLL
SGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLG
EDGSVQIADFGVSAFLAGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKY
PPMKVLMLTLQNDPPSLETEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFF

>2vwi-a1-m1-cC (length=270) [Search sequence]

PWSINRDDYELQEVIGSGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMS
QCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILR
EVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVGTPCWM
APEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETKKYG
KSFRKMISLCLQKDPEKRPTAAELLRHKFF

Structure information

PDB ID	2vwi (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Structure of the OSR1 kinase, a hypertension drug target
Assembly ID	1
Resolution	2.15Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	34
Sequence identity between the two chains	0.987
PubMed citation	18831043

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	A	C
UniProt accession	O95747	O95747
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:2vwiA	BioLiP:2vwiC

3D structure

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Dimer structure: Chain 1 in red; Chain 2 in blue.

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Download:	2vwi-a1-m1-cA_2vwi-a1-m1-cC.pdb.gz

Full biological assembly

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Download:	2vwi-assembly1.cif.gz