2wns/1/1:A/1:B

Sequences

>2wns-a1-m1-cA (length=197) [Search sequence]

ALGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRPRLLSQVADILFQTAQNAGI SFDTVCGVPYTALPLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGETCLIIEDVV TSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKMLEILEQQ KKVDAETVGRVKRFIQE

>2wns-a1-m1-cB (length=199) [Search sequence]

LGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRPRLLSQVADILFQTAQNAGIS FDTVCGVPYTALPLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGETCLIIEDVVT SGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKMLEILEQQK KVDAETVGRVKRFIQEAHH

Structure information

PDB ID	2wns (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Human Orotate phosphoribosyltransferase (OPRTase) domain of Uridine 5' -monophosphate synthase (UMPS) in complex with its substrate orotidine 5'-monophosphate (OMP)
Assembly ID	1
Resolution	1.9Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	89
Sequence identity between the two chains	0.995
PubMed citation

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	A	B
UniProt accession	P11172	P11172
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:2wnsA	BioLiP:2wnsB

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 2wns-a1-m1-cA_2wns-a1-m1-cB.pdb.gz

Full biological assembly Download: 2wns-assembly1.cif.gz