2x2n/2/1:C/1:A

Sequences

>2x2n-a2-m1-cC (length=441) [Search sequence]

TDPPVYPVTVPILGHIIQFGKSPLGFMQECKRQLKSGIFTINIVGKRVTIVGDPHEHSRF FLPRNEVLSPREVYSFMVPVFGEGVAYAAPYPRMREQLNFLAEELTIAKFQNFVPAIQHE VRKFMAANWDKDEGEINLLEDCSTMIINTACQCLFGEDLRKRLDARRFAQLLAKMESSLI PAAVFLPILLKLPLPQSARCHEARTELQKILSEIIIARKAATSDLLSGLLSAVYRDGTPM SLHEVCGMIVAAMFAGQHTSSITTTWSMLHLMHPANVKHLEALRKEIEEFPAQLNYNNVM DEMPFAERCARESIRRDPPLLMLMRKVMADVKVGSYVVPKGDIIACSPLLSHHDEEAFPE PRRWDPERDEKVEGAFIGFGAGVHKCIGQKFGLLQVKTILATAFRSYDFQLLRDEVPDPD YHTMVVGPTASQCRVKYIRRK

>2x2n-a2-m1-cA (length=448) [Search sequence]

TDPPVYPVTVPILGHIIQFGKSPLGFMQECKRQLKSGIFTINIVGKRVTIVGDPHEHSRF FLPRNEVLSPREVYSFMVPVFGEGVAYAAPYPRMREQLNFLAEELTIAKFQNFVPAIQHE VRKFMAANWDKDEGEINLLEDCSTMIINTACQCLFGEDLRKRLDARRFAQLLAKMESSLI PAAVFLPILLKLPLPQSARCHEARTELQKILSEIIIARKAAAVNKSSTSDLLSGLLSAVY RDGTPMSLHEVCGMIVAAMFAGQHTSSITTTWSMLHLMHPANVKHLEALRKEIEEFPAQL NYNNVMDEMPFAERCARESIRRDPPLLMLMRKVMADVKVGSYVVPKGDIIACSPLLSHHD EEAFPEPRRWDPERDEKVEGAFIGFGAGVHKCIGQKFGLLQVKTILATAFRSYDFQLLRD EVPDPDYHTMVVGPTASQCRVKYIRRKA

Structure information

PDB ID	2x2n (database links: RCSB PDB PDBe PDBj PDBsum)
Title	X-ray structure of cyp51 from trypanosoma brucei in complex with posaconazole in two different conformations
Assembly ID	2
Resolution	2.6Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	81
Sequence identity between the two chains	1.0
PubMed citation	20386598

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	C	A
UniProt accession	Q385E8	Q385E8
Species	5691 (Trypanosoma brucei)	5691 (Trypanosoma brucei)
Function annotation	BioLiP:2x2nC	BioLiP:2x2nA

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 2x2n-a2-m1-cC_2x2n-a2-m1-cA.pdb.gz

Full biological assembly Download: 2x2n-assembly2.cif.gz

Similar dimers

Other dimers with similar sequences but different poses

3tik/3/1:B/1:C 3tik/1/1:A/1:D 3tik/1/1:B/1:C 3tik/2/1:A/1:D