2zm3/5/1:B/6:C

Sequences
>2zm3-a5-m1-cB (length=296) [Search sequence]
SFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAA
SMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEAP
PSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIETDRKG
GKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGG
LLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEEN
>2zm3-a5-m6-cC (length=296) [Search sequence]
SFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAA
SMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPLAP
PSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIETDRKG
GKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGG
LLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEEN
Structure information
PDB ID 2zm3 (database links: RCSB PDB PDBe PDBj PDBsum)
Title Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor
Assembly ID 5
Resolution 2.5Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 10
Sequence identity between the two chains 0.997
PubMed citation 18501599
Chain information
Chain 1 Chain 2
Model ID 1 6
Chain ID B C
UniProt accession P08069 P08069
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:2zm3B BioLiP:2zm3C
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 2zm3-a5-m1-cB_2zm3-a5-m6-cC.pdb.gz
Full biological assembly
Download: 2zm3-assembly5.cif.gz
Similar dimers
Other dimers with similar sequences and structures 2zm3/5/1:C/6:B 2zm3/5/4:D/3:A 2zm3/5/5:D/2:A
Other dimers with similar sequences but different poses
  • 3f5p/17/2:L/2:R 2zm3/5/1:B/1:C 2zm3/5/1:C/3:A 2zm3/5/4:D/2:A 2zm3/5/4:D/6:B 2zm3/5/5:D/1:B 2zm3/5/5:D/3:A 2zm3/5/6:B/6:C 2zm3/5/6:C/2:A 3f5p/17/1:D/1:C 3f5p/17/1:D/1:G 3f5p/17/1:G/1:H 3f5p/17/1:H/1:C 3f5p/17/2:K/2:M 3f5p/17/2:K/2:R 3f5p/17/2:L/2:M
  • 3f5p/17/2:L/1:H 2zm3/5/1:B/6:B 2zm3/5/2:A/3:A 2zm3/5/4:D/1:C 2zm3/5/5:D/6:C 3f5p/17/2:K/1:D 3f5p/17/2:M/1:C 3f5p/17/2:R/1:G
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