3c4f/3/1:A/2:A

Sequences
>3c4f-a3-m1-cA (length=290) [Search sequence]
ELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEK
DLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPEEQL
SSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYK
KTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKE
GHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE
>3c4f-a3-m2-cA (length=290) [Search sequence]
ELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEK
DLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPEEQL
SSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYK
KTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKE
GHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE
Structure information
PDB ID 3c4f (database links: RCSB PDB PDBe PDBj PDBsum)
Title FGFR TYROSINE KINASE DOMAIN IN COMPLEX WITH 3-(3-methoxybenzyl)-7-azaindole
Assembly ID 3
Resolution 2.07Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 37
Sequence identity between the two chains 1.0
PubMed citation 18287029
Chain information
Chain 1 Chain 2
Model ID 1 2
Chain ID A A
UniProt accession P11362 P11362
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:3c4fA BioLiP:3c4fA
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 3c4f-a3-m1-cA_3c4f-a3-m2-cA.pdb.gz
Full biological assembly
Download: 3c4f-assembly3.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 3js2/2/1:B/1:A 3js2/1/1:B/1:A
  • 3kxx/6/1:C/1:B 3kxx/5/1:D/1:A
  • 4nka/1/1:A/1:B 4nk9/1/1:A/1:B 5vnd/3/1:B/1:A
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