3ciz/3/1:A/2:B

Sequences
>3ciz-a3-m1-cA (length=562) [Search sequence]
HHMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYATTSRSAGLRQKKVTFDRLQV
LDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSKFGYGAKDVRNLSSKAVNHI
HSVWKDLLEDTVTPIDTTIMAKNEVFCVQPEGRKPARLIVFPDLGVRVCEKMALYDVVST
LPQVVMGSSYGFQYSPGQRVEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQ
CCDLAPEARQAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKASA
ACRAAKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPPGDPPQPEYDLE
LITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIMYAPTLWA
RMILMTHFFSILLAQEQLEKALDCQIYGACYSIEPLDLPQIIERLHGLSAFSLHSYSPGE
INRVASCLRKLGVPPLRVWRHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKLTPIPA
ASRLDLSGWFVAGYSGGDIYHS
>3ciz-a3-m2-cB (length=563) [Search sequence]
HHMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYATTSRSAGLRQKKVTFDRLQV
LDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSKFGYGAKDVRNLSSKAVNHI
HSVWKDLLEDTVTPIDTTIMAKNEVFCVQPEGRKPARLIVFPDLGVRVCEKMALYDVVST
LPQVVMGSSYGFQYSPGQRVEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQ
CCDLAPEARQAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKASA
ACRAAKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPPGDPPQPEYDLE
LITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIMYAPTLWA
RMILMTHFFSILLAQEQLEKALDCQIYGACYSIEPLDLPQIIERLHGLSAFSLHSYSPGE
INRVASCLRKLGVPPLRVWRHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKLTPIPA
ASRLDLSGWFVAGYSGGDIYHSL
Structure information
PDB ID 3ciz (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments
Assembly ID 3
Resolution 1.87Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 22
Sequence identity between the two chains 1.0
PubMed citation 18400495
Chain information
Chain 1 Chain 2
Model ID 1 2
Chain ID A B
UniProt accession P26663 P26663
Species 31647 (Hepatitis C virus subtype 1b) 31647 (Hepatitis C virus subtype 1b)
Function annotation BioLiP:3cizB
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 3ciz-a3-m1-cA_3ciz-a3-m2-cB.pdb.gz
Full biological assembly
Download: 3ciz-assembly3.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 1gx5/1/1:A/2:A 1csj/1/1:A/1:B 1gx6/1/1:A/2:A 2wrm/1/1:A/2:A
  • 1yvf/2/1:A/2:A 1z4u/2/1:A/2:A
  • 3mf5/2/1:A/1:B 3mf5/1/1:A/1:B
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