3cl9/3/2:A/4:A

Sequences

>3cl9-a3-m2-cA (length=505) [Search sequence]

SLFKIRMPETVAEGTRLALRAFSLVVAVDERGGIGDGRSIPWNVPEDMKFFRDVTTKLRG
KNVKPSPAKRNAVVMGRKTWDSIPPKFRPLPGRLNVVLSSTLTTQHLLDNLHADSIVAVN
GGLEQALQLLASPNYTPSIETVYCIGGGSVYAEALRPPCVHLLQAIYRTTIRASESSCSV
FFRVPESGTEAAAGIEWQRETISEELTSANGNETKYYFEKLIPRNREEEQYLSLVDRIIR
EGNVKHDRTGVGTLSIFGAQMRFSLRNNRLPLLTTKRVFWRGVCEELLWFLRGETYAKKL
SDKGVHIWDDNGSRAFLDSRGLTEYEEMDLGPVYGFQWRHFGAAYTHHDANYDGQGVDQI
KAIVETLKTNPDDRRMLFTAWNPSALPRMALPPCHLLAQFYVSNGELSCMLYQRSCDMGL
GVPFNIASYALLTILIAKATGLRPGELVHTLGDAHVYSNHVEPCNEQLKRVPRAFPYLVF
RREREFLEDYEEGDMEVIDYAPYPP

>3cl9-a3-m4-cA (length=505) [Search sequence]

Structure information

PDB ID	3cl9 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Structure of bifunctional TcDHFR-TS in complex with MTX
Assembly ID	3
Resolution	3.3Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	35
Sequence identity between the two chains	1.0
PubMed citation	18536013

Chain information

	Chain 1	Chain 2
Model ID	2	4
Chain ID	A	A
UniProt accession	Q27793	Q27793
Species	5693 (Trypanosoma cruzi)	5693 (Trypanosoma cruzi)
Function annotation	BioLiP:3cl9A	BioLiP:3cl9A

3D structure

Switch viewer: [NGL] [JSmol]

Dimer structure: Chain 1 in red; Chain 2 in blue.

Download:

3cl9-a3-m2-cA_3cl9-a3-m4-cA.pdb.gz

Full biological assembly

Download:

3cl9-assembly3.cif.gz

Similar dimers

Other dimers with similar sequences and structures	3cl9/2/1:A/3:A 3cl9/3/1:A/3:A
Other dimers with similar sequences but different poses	3cl9/3/1:A/4:A 2h2q/1/1:B/1:A 3cl9/3/2:A/3:A 3irm/2/1:D/1:C 2h2q/2/2:B/1:A 3cl9/1/1:A/2:A 3cl9/3/1:A/2:A 3cl9/3/3:A/4:A 3clb/1/1:D/1:A 3clb/2/1:B/1:C 3hbb/1/1:D/1:A 3hbb/2/1:B/1:C 3inv/1/1:B/1:A 3irm/1/1:B/1:A 3irn/1/1:A/1:B 3irn/2/1:D/1:C 3iro/1/1:B/1:A 3iro/2/1:D/1:C 3kjs/1/1:A/1:D 3kjs/2/1:B/1:C 5t7o/1/1:A/1:B 5t7o/2/1:C/1:D