3gwc/2/1:H/1:E

Sequences
>3gwc-a2-m1-cH (length=243) [Search sequence]
ETAPLRVQLIAKTDFLAPPDVPWTTDADGGPALVEFAGRACYQSWSKPNPKTATNAGYLR
HIIDVGHFSVLEHASVSFYITGISRSCTHELIRHRHFSYSQLSQRYVPEKDSRVVVPPGM
EDDADLRHILTEAADAARATYSELLAKLEAKFADQPNAILRRKQARQAARAVLPNATETR
IVVTGNYRAWRHFIAMRASEHADVEIRRLAIECLRQLAAVAPAVFADFEVTTLADGTEVA
TSP
>3gwc-a2-m1-cE (length=244) [Search sequence]
AETAPLRVQLIAKTDFLAPPDVPWTTDADGGPALVEFAGRACYQSWSKPNPKTATNAGYL
RHIIDVGHFSVLEHASVSFYITGISRSCTHELIRHRHFSYSQLSQRYVPEKDSRVVVPPG
MEDDADLRHILTEAADAARATYSELLAKLEAKFADQPNAILRRKQARQAARAVLPNATET
RIVVTGNYRAWRHFIAMRASEHADVEIRRLAIECLRQLAAVAPAVFADFEVTTLADGTEV
ATSP
Structure information
PDB ID 3gwc (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal structure of Mycobacterium tuberculosis thymidylate synthase X bound to FdUMP and FAD
Assembly ID 2
Resolution 1.9Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 127
Sequence identity between the two chains 1.0
PubMed citation 25613812
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID H E
UniProt accession P9WG57 P9WG57
Species 1773 (Mycobacterium tuberculosis) 1773 (Mycobacterium tuberculosis)
Function annotation BioLiP:3gwcH BioLiP:3gwcE
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 3gwc-a2-m1-cH_3gwc-a2-m1-cE.pdb.gz
Full biological assembly
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Download: 3gwc-assembly2.cif.gz
Similar dimers
Other dimers with similar sequences and structures 2af6/10/1:D/1:A 2af6/1/1:C/1:B 2af6/1/1:D/1:A 2af6/2/1:E/1:H 2af6/2/1:F/1:G 2af6/7/1:E/1:H 2af6/8/1:C/1:B 2af6/9/1:F/1:G 2gq2/1/1:C/1:B 2gq2/1/1:D/1:A 3gwc/1/1:B/1:C 3gwc/1/1:D/1:A 3gwc/2/1:F/1:G 3hzg/1/1:A/1:D 3hzg/1/1:B/1:C 3hzg/2/1:A/1:D 3hzg/4/1:B/1:C
Other dimers with similar sequences but different poses
  • 3gwc/2/1:E/1:G 2af6/1/1:C/1:A 2af6/1/1:D/1:B 2af6/2/1:E/1:G 2af6/2/1:F/1:H 2af6/3/1:F/1:H 2af6/4/1:E/1:G 2af6/5/1:D/1:B 2af6/6/1:C/1:A 2gq2/1/1:C/1:A 3gwc/1/1:B/1:D 3gwc/1/1:C/1:A 3gwc/2/1:F/1:H 3hzg/1/1:A/1:C 3hzg/1/1:B/1:D 3hzg/3/1:A/1:C 3hzg/5/1:B/1:D
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