3h4v/1/1:D/1:A

Sequences
>3h4v-a1-m1-cD (length=263) [Search sequence]
TVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQA
DLSNVATAPVAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRREAMETATAD
LFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALE
GLTRSAALELAPLQIRVNGVGPGLSVLVDDMVWEGHRSKVPLYQRDSSAAEVSDVVIFLC
SSKAKYITGTCVKVDGGYSLTRA
>3h4v-a1-m1-cA (length=273) [Search sequence]
TVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQA
DLSNVATAPVADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNGDREA
METATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYT
MAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVWEGHRSKVPLYQRDSSAA
EVSDVVIFLCSSKAKYITGTCVKVDGGYSLTRA
Structure information
PDB ID 3h4v (database links: RCSB PDB PDBe PDBj PDBsum)
Title Selective screening and design to identify inhibitors of leishmania major pteridine reductase 1
Assembly ID 1
Resolution 2.4Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 32
Sequence identity between the two chains 1.0
PubMed citation 18245389
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID D A
UniProt accession Q01782 Q01782
Species 5664 (Leishmania major) 5664 (Leishmania major)
Function annotation BioLiP:3h4vD BioLiP:3h4vA
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 3h4v-a1-m1-cD_3h4v-a1-m1-cA.pdb.gz
Full biological assembly
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Download: 3h4v-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences and structures 1e7w/1/1:B/2:A 1e7w/1/2:B/1:A 1e92/1/1:C/1:B 1e92/1/1:D/1:A 1w0c/1/1:C/1:B 1w0c/1/1:D/1:A 1w0c/2/1:G/1:F 1w0c/2/1:H/1:E 2bf7/1/1:C/1:B 2bf7/1/1:D/1:A 2bfa/1/1:C/1:B 2bfa/1/1:D/1:A 2bfm/1/1:C/1:B 2bfm/1/1:D/1:A 2bfo/1/1:C/1:B 2bfo/1/1:D/1:A 2bfp/1/1:C/1:B 2bfp/1/1:D/1:A 2qhx/1/1:C/1:B 2qhx/1/1:D/1:A 3h4v/1/1:C/1:B 3h4v/2/1:G/1:F 3h4v/2/1:H/1:E 5l42/1/1:C/1:B 5l42/1/1:D/1:A 5l4n/1/1:A/1:D 5l4n/1/1:B/1:C 6rxc/1/1:B/1:C 6rxc/1/1:D/1:A 7pxx/1/1:C/1:B 7pxx/1/1:D/1:A
Other dimers with similar sequences but different poses
  • 2bfp/1/1:C/1:A 1e7w/1/1:A/2:A 1e7w/1/1:B/2:B 1e92/1/1:C/1:A 1e92/1/1:D/1:B 1w0c/1/1:C/1:A 1w0c/1/1:D/1:B 1w0c/2/1:G/1:E 1w0c/2/1:H/1:F 2bf7/1/1:C/1:A 2bf7/1/1:D/1:B 2bfa/1/1:C/1:A 2bfa/1/1:D/1:B 2bfm/1/1:C/1:A 2bfm/1/1:D/1:B 2bfo/1/1:C/1:A 2bfo/1/1:D/1:B 2bfp/1/1:D/1:B 2qhx/1/1:C/1:A 2qhx/1/1:D/1:B 3h4v/1/1:C/1:A 3h4v/1/1:D/1:B 3h4v/2/1:G/1:E 3h4v/2/1:H/1:F 5l42/1/1:C/1:A 5l42/1/1:D/1:B 5l4n/1/1:A/1:C 5l4n/1/1:B/1:D 6rxc/1/1:C/1:A 6rxc/1/1:D/1:B 7pxx/1/1:C/1:A 7pxx/1/1:D/1:B
  • 7pxx/1/1:D/1:C 1e7w/1/1:B/1:A 1e7w/1/2:B/2:A 1e92/1/1:B/1:A 1e92/1/1:D/1:C 1w0c/1/1:B/1:A 1w0c/1/1:D/1:C 1w0c/2/1:E/1:F 1w0c/2/1:H/1:G 2bf7/1/1:A/1:B 2bf7/1/1:C/1:D 2bfa/1/1:A/1:B 2bfa/1/1:C/1:D 2bfm/1/1:A/1:B 2bfm/1/1:C/1:D 2bfo/1/1:B/1:A 2bfo/1/1:C/1:D 2bfp/1/1:B/1:A 2bfp/1/1:C/1:D 2qhx/1/1:A/1:B 2qhx/1/1:C/1:D 3h4v/1/1:A/1:B 3h4v/1/1:C/1:D 3h4v/2/1:E/1:F 3h4v/2/1:G/1:H 5l42/1/1:A/1:B 5l42/1/1:D/1:C 5l4n/1/1:A/1:B 5l4n/1/1:D/1:C 6rxc/1/1:B/1:A 6rxc/1/1:D/1:C 7pxx/1/1:A/1:B
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