3i6u/1/1:B/1:A

Sequences

>3i6u-a1-m1-cB (length=376) [Search sequence]

TPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSKKHFRIFR EVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNKVFVFFDLTVDD QSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIRIISKRKFAIGLNVETEIEI LKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQ YLHENGIIHRDLKPENVLLSSQEEDCLIKITDFPTYLAPEVLVNRAVDCWSLGVILFICL SGYPPFSEVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPW LQDEDMKRKFQDLLSE

>3i6u-a1-m1-cA (length=390) [Search sequence]

TPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSKKHFRIFR EVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNKVFVFFDLTVDD QSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIRIISKRKFAIGLNVETEIEI LKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQ YLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGPTYLAPEVLVAGYNRAVDCW SLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDP KARFTTEEALRHPWLQDEDMKRKFQDLLSE

Structure information

PDB ID	3i6u (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Structure and Activation Mechanism of the CHK2 DNA-Damage Checkpoint Kinase
Assembly ID	1
Resolution	3Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	131
Sequence identity between the two chains	1.0

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	B	A
UniProt accession	O96017	O96017
Species	9606 (Homo sapiens)	9606 (Homo sapiens)

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 3i6u-a1-m1-cB_3i6u-a1-m1-cA.pdb.gz

Full biological assembly Download: 3i6u-assembly1.cif.gz