3j8h/1/1:E/1:G |
| >3j8h-a1-m1-cE (length=3660) [Search sequence] |
QFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFTLEQ
SLSVRALQEMLANGHRTLLYGHAILLRHAHSRMYLSCLTTSRKLAFDVGLQEDATGEACW
WTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTLQVDASFMQTLWNMNPICSCCEE
GYVTGGHVLRLFHGECLTISAADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSHL
RWGQPLRIRHVTTGRYLALTEDQGLVVVDACKAHTKATSFCFRVSKEKLKRDVEGMGPPE
IKYGESLCFVQHVASGLWLTYAAVLKKKAILHQEGHMDDALFLTRCQQEESQAARMIHST
AGLYNQFIKGLDSFSGKPRLPIEAVILSLQDLIGYFEPPSEELQHEEKQSKLRSLRNRQS
LFQEEGMLSLVLNCIDRLNVYTTYAGEEAAESWKEIVNLLYELLASLIRGNRANCALFST
NLDWVVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDV
LCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGGKWYFEVMVDE
VVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPV
TSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLDGLFFPVVSFSAGVKVR
FLLGEFKFLPPPGYAPCHEAVLPRERLRLEPIKEYRREGPRGPHLVGPSRCFVPCPVDTV
QIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVNFHSLPEPERN
YNLQMSGETLKTLLALGCHVGMADEKAYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAEN
GHNVWARDRVAQRRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPRVRIFRAE
KSYTVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSEP
FGRPWQSGDVVGCMIDLTENTIIFTLNGEVLAFREIEIGDGFLPVCSLGPGQVGHLNLGQ
DVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPPEHPHYEVARMDLAHRT
WGSQNSLVEMLFLRLSLPVQFTYYYSVRVFACVWVGWVTPDYHQHDMNFDLSVTVTMGDE
QGNVHSSLKCSNXXXXXSHTDLVIGCLVGLMTFTANGKESNTFFQVEPNTKLFPAVFVLP
THQNVIQFEAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVETRRAGERLGWA
VQCQDPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNNRVAHALCS
HVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITL
FPPGLPGVGVTTSLRPPHHFSPPCFVALSPAIPLEALRDKALRMLGEAVRDGGQHARDPV
GGSVEFQFVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEGLLQMKLPESVKLQMCNLLEY
FCDQELQHRVESLAAFAERYVDKLQANQRSRXXXXXXXXXXXXXXXTSLSSRLRSLLETV
RLSLQELVSHMVVRWAQEDYVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVE
DTMSLLECLGQIRSLLIVQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNV
LGPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGITPLDVAAASVIDNNELALAL
QEQDLEKVVSYLAGCGLPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPEGLLAA
IEEAIRIGHAIMSFYAALIDLLGRCAEALRIRAILRSLXXXXXXXXXXXXXXFVPDHKAS
MVLFLDRVYNQDFLLHVLVGFLPDMRAAASLTEMALALNRYLCLAVLPLIXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNFDPRP
VETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENVDEELKTHPMLRPYKTFSE
KDKEIYRWPIKESLKAMIAWEWTIEKAREGEYDPREGYNPQPPDLSGVTLSRELQAMAEQ
LAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAV
TRGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPTHRACN
MFLESYKAAWILTEDHSFEDRMIDDLSKAKPDPLHQLVLHFSRTALTEKSKLDEDYLYMA
YADIMAKSCEVSFEEKEMEKQRLLYQQSRLHTRGAAEMVLQMISACKGETGAMVSSTLKL
GISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKDDEFTQDL
FRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIE
EQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLA
QDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDM
IVGSEAFQDYVTDPRGLISKKDFQKAMDSQQFTGPEIQFLLSCSEADENEMINFEEFANR
PARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIY
FEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQIEVQ
RVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSVYYFLEESTGYMEPALWCLSLLHT
LVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPGDDDVKGQWDRLVLNTPSF
PSNYWDKFVKRKVLDKHGDIFGRERIAELLGLTWLMSIDVKYQIWKFGVIFTDNSFLYLG
WYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTV
VAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYR
VVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPH
GFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYE |
| >3j8h-a1-m1-cG (length=3660) [Search sequence] |
QFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFTLEQ
SLSVRALQEMLANGHRTLLYGHAILLRHAHSRMYLSCLTTSRKLAFDVGLQEDATGEACW
WTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTLQVDASFMQTLWNMNPICSCCEE
GYVTGGHVLRLFHGECLTISAADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSHL
RWGQPLRIRHVTTGRYLALTEDQGLVVVDACKAHTKATSFCFRVSKEKLKRDVEGMGPPE
IKYGESLCFVQHVASGLWLTYAAVLKKKAILHQEGHMDDALFLTRCQQEESQAARMIHST
AGLYNQFIKGLDSFSGKPRLPIEAVILSLQDLIGYFEPPSEELQHEEKQSKLRSLRNRQS
LFQEEGMLSLVLNCIDRLNVYTTYAGEEAAESWKEIVNLLYELLASLIRGNRANCALFST
NLDWVVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDV
LCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGGKWYFEVMVDE
VVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPV
TSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLDGLFFPVVSFSAGVKVR
FLLGEFKFLPPPGYAPCHEAVLPRERLRLEPIKEYRREGPRGPHLVGPSRCFVPCPVDTV
QIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVNFHSLPEPERN
YNLQMSGETLKTLLALGCHVGMADEKAYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAEN
GHNVWARDRVAQRRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPRVRIFRAE
KSYTVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSEP
FGRPWQSGDVVGCMIDLTENTIIFTLNGEVLAFREIEIGDGFLPVCSLGPGQVGHLNLGQ
DVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPPEHPHYEVARMDLAHRT
WGSQNSLVEMLFLRLSLPVQFTYYYSVRVFACVWVGWVTPDYHQHDMNFDLSVTVTMGDE
QGNVHSSLKCSNXXXXXSHTDLVIGCLVGLMTFTANGKESNTFFQVEPNTKLFPAVFVLP
THQNVIQFEAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVETRRAGERLGWA
VQCQDPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNNRVAHALCS
HVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITL
FPPGLPGVGVTTSLRPPHHFSPPCFVALSPAIPLEALRDKALRMLGEAVRDGGQHARDPV
GGSVEFQFVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEGLLQMKLPESVKLQMCNLLEY
FCDQELQHRVESLAAFAERYVDKLQANQRSRXXXXXXXXXXXXXXXTSLSSRLRSLLETV
RLSLQELVSHMVVRWAQEDYVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVE
DTMSLLECLGQIRSLLIVQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNV
LGPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGITPLDVAAASVIDNNELALAL
QEQDLEKVVSYLAGCGLPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPEGLLAA
IEEAIRIGHAIMSFYAALIDLLGRCAEALRIRAILRSLXXXXXXXXXXXXXXFVPDHKAS
MVLFLDRVYNQDFLLHVLVGFLPDMRAAASLTEMALALNRYLCLAVLPLIXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNFDPRP
VETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENVDEELKTHPMLRPYKTFSE
KDKEIYRWPIKESLKAMIAWEWTIEKAREGEYDPREGYNPQPPDLSGVTLSRELQAMAEQ
LAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAV
TRGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPTHRACN
MFLESYKAAWILTEDHSFEDRMIDDLSKAKPDPLHQLVLHFSRTALTEKSKLDEDYLYMA
YADIMAKSCEVSFEEKEMEKQRLLYQQSRLHTRGAAEMVLQMISACKGETGAMVSSTLKL
GISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKDDEFTQDL
FRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIE
EQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLA
QDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDM
IVGSEAFQDYVTDPRGLISKKDFQKAMDSQQFTGPEIQFLLSCSEADENEMINFEEFANR
PARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIY
FEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQIEVQ
RVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSVYYFLEESTGYMEPALWCLSLLHT
LVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPGDDDVKGQWDRLVLNTPSF
PSNYWDKFVKRKVLDKHGDIFGRERIAELLGLTWLMSIDVKYQIWKFGVIFTDNSFLYLG
WYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTV
VAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYR
VVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPH
GFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYE |
|
| PDB ID |
3j8h (database links:
RCSB PDB
PDBe
PDBj
PDBsum) |
| Title |
Structure of the rabbit ryanodine receptor RyR1 in complex with FKBP12 at 3.8 Angstrom resolution |
| Assembly ID |
1 |
| Resolution |
3.8Å |
| Method of structure determination |
ELECTRON MICROSCOPY |
| Number of inter-chain contacts |
230 |
| Sequence identity between the two chains |
1.0 |
| PubMed citation |
25517095 |
|
|
Chain 1 |
Chain 2 |
| Model ID |
1 |
1 |
| Chain ID |
E |
G |
| UniProt accession |
P11716 |
P11716 |
| Species |
9986 (Oryctolagus cuniculus) |
9986 (Oryctolagus cuniculus) |
| Function annotation |
BioLiP:3j8hE |
BioLiP:3j8hG |
|
Switch viewer: [NGL] [JSmol]
|
Dimer structure:
Chain 1 in red;
Chain 2 in blue.
|
Full biological assembly
|
|
| Other dimers with similar sequences and structures |
3j8h/1/1:A/1:C 3j8h/1/1:A/1:G 3j8h/1/1:C/1:E |
|