3kex/2/2:B/1:A

Sequences

>3kex-a2-m2-cB (length=283) [Search sequence]

KVLARIFKETELRKLKVLGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVT
DHMLAIGSLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQ
IAKGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDKQTPIKWMALESIH
FGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVM
VKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKREGPGIAP

>3kex-a2-m1-cA (length=292) [Search sequence]

KVLARIFKETELRKLKVLGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVT
DHMLAIGSLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQ
IAKGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDKQLLTPIKWMALES
IHFGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYM
VMVKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKRESGPGIAPGPEPHG

Structure information

PDB ID	3kex (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal structure of the catalytically inactive kinase domain of the human epidermal growth factor receptor 3 (HER3)
Assembly ID	2
Resolution	2.797Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	44
Sequence identity between the two chains	1.0
PubMed citation	20007378

Chain information

	Chain 1	Chain 2
Model ID	2	1
Chain ID	B	A
UniProt accession	P21860	P21860
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:3kexB	BioLiP:3kexA

3D structure

Switch viewer: [NGL] [JSmol]

Dimer structure: Chain 1 in red; Chain 2 in blue.

Download:

3kex-a2-m2-cB_3kex-a2-m1-cA.pdb.gz

Full biological assembly

Download:

3kex-assembly2.cif.gz