3ld6/2/2:B/1:A

Sequences

>3ld6-a2-m2-cB (length=444) [Search sequence]

VKSPPYIFSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALL FNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPVFLEQKKMLKSGLNIAHFKQHVSIIEK ETKEYFESWGESGEKNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFSHA AWLLPGWLPLPSFRRRDRAHREIKDIFYKAIQKRRQSQEKIDDILQTLLDATYKDGRPLT DDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQL KDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWVE RLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDG YFPTVNYTTMIHTPENPVIRYKRR

>3ld6-a2-m1-cA (length=445) [Search sequence]

VKSPPYIFSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALL FNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPVFLEQKKMLKSGLNIAHFKQHVSIIEK ETKEYFESWGESGEKNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFSHA AWLLPGWLPLPSFRRRDRAHREIKDIFYKAIQKRRQSQEKIDDILQTLLDATYKDGRPLT DDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQL KDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWVE RLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDG YFPTVNYTTMIHTPENPVIRYKRRS

Structure information

PDB ID	3ld6 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal structure of human lanosterol 14alpha-demethylase (CYP51) in complex with ketoconazole
Assembly ID	2
Resolution	2.8Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	23
Sequence identity between the two chains	1.0
PubMed citation	20149798

Chain information

	Chain 1	Chain 2
Model ID	2	1
Chain ID	B	A
UniProt accession	Q16850	Q16850
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:3ld6B	BioLiP:3ld6A

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 3ld6-a2-m2-cB_3ld6-a2-m1-cA.pdb.gz

Full biological assembly Download: 3ld6-assembly2.cif.gz

Similar dimers

Other dimers with similar sequences but different poses

4uhi/1/1:C/1:D 4uhi/1/1:A/1:B 4uhi/1/1:A/1:D 4uhi/1/1:B/1:C