3mf5/2/1:A/1:B |
| >3mf5-a2-m1-cA (length=557) [Search sequence] |
HMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYATTSRSAGLRQKKVTFDRLQVL
DDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSKFGYGAKDVRNLSSKAVNHIH
SVWKDLLEDTVTPIDTTIMAKNEVFCVQRKPARLIVFPDLGVRVCEKMALYDVVSTLPQV
VMGSSYGFQYSPGQRVEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDL
APEARQAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKASAACRA
AKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPPGDPPQPEYDLELITS
CSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIMYAPTLWARMIL
MTHFFSILLAQEQLEKALDCQIYGACYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRV
ASCLRKLGVPPLRVWRHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKLTPIPAASRL
DLSGWFVAGYSGGDIYH |
| >3mf5-a2-m1-cB (length=557) [Search sequence] |
HMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYATTSRSAGLRQKKVTFDRLQVL
DDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSKFGYGAKDVRNLSSKAVNHIH
SVWKDLLEDTVTPIDTTIMAKNEVFCVQRKPARLIVFPDLGVRVCEKMALYDVVSTLPQV
VMGSSYGFQYSPGQRVEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDL
APEARQAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKASAACRA
AKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPPGDPPQPEYDLELITS
CSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIMYAPTLWARMIL
MTHFFSILLAQEQLEKALDCQIYGACYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRV
ASCLRKLGVPPLRVWRHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKLTPIPAASRL
DLSGWFVAGYSGGDIYH |
|
| PDB ID |
3mf5 (database links:
RCSB PDB
PDBe
PDBj
PDBsum) |
| Title |
Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor |
| Assembly ID |
2 |
| Resolution |
2Å |
| Method of structure determination |
X-RAY DIFFRACTION |
| Number of inter-chain contacts |
39 |
| Sequence identity between the two chains |
1.0 |
| PubMed citation |
20584604 |
|
|
Chain 1 |
Chain 2 |
| Model ID |
1 |
1 |
| Chain ID |
A |
B |
| UniProt accession |
P26663 |
P26663 |
| Species |
11105 (Hepatitis C virus (isolate BK)) |
11105 (Hepatitis C virus (isolate BK)) |
| Function annotation |
BioLiP:3mf5A |
BioLiP:3mf5B |
|
Switch viewer: [NGL] [JSmol]
|
Dimer structure:
Chain 1 in red;
Chain 2 in blue.
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Full biological assembly
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