3oom/1/1:A/2:A

Sequences
>3oom-a1-m1-cA (length=297) [Search sequence]
TVARDITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENI
LGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIE
IFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYM
APEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFE
DMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKID
>3oom-a1-m2-cA (length=297) [Search sequence]
TVARDITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENI
LGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIE
IFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYM
APEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFE
DMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKID
Structure information
PDB ID 3oom (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00507
Assembly ID 1
Resolution 2Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 35
Sequence identity between the two chains 1.0
PubMed citation
Chain information
Chain 1 Chain 2
Model ID 1 2
Chain ID A A
UniProt accession Q04771 Q04771
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:3oomA BioLiP:3oomA
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Color: [By chain]   [By residue index]  
Spin: [Spin off]   [Spin on]   [Reset]
Render: [Low quality]   [High quality]  
Background: [Black]   [White]  
Download: 3oom-a1-m1-cA_3oom-a1-m2-cA.pdb.gz
Full biological assembly
Download: 3oom-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 5s8a/1/1:A/2:B 3q4u/1/1:A/1:B 3q4u/2/1:C/2:D 3q4u/3/3:C/1:D 5s7k/1/1:A/2:B 5s7l/1/1:A/2:B 5s7q/1/1:A/2:B 5s7t/1/1:A/2:B 5s7w/1/1:A/2:B 5s83/1/1:A/2:B 5s86/1/1:A/2:B 5s8b/1/1:A/2:B 5s9k/1/1:A/2:B
    		•

    [Back to Home]