3os3/2/1:A/2:A

Sequences

>3os3-a2-m1-cA (length=272) [Search sequence]

ELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHEC
NSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLR
EKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYS
VQSDIWSMGLSLVEMAVGRYPIPMAIFELLDYIVNEPPPKLPVFSLEFQDFVNKCLIKNP
AERADLKQLMVHAFIKRSDAEEVDFAGWLCST

>3os3-a2-m2-cA (length=272) [Search sequence]

Structure information

PDB ID	3os3 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Mitogen-activated protein kinase kinase 1 (MEK1) in complex with CH4858061 and MgATP
Assembly ID	2
Resolution	2.8Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	90
Sequence identity between the two chains	1.0
PubMed citation	21316218

Chain information

	Chain 1	Chain 2
Model ID	1	2
Chain ID	A	A
UniProt accession	Q02750	Q02750
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:3os3A	BioLiP:3os3A

3D structure

Switch viewer: [NGL] [JSmol]

Dimer structure: Chain 1 in red; Chain 2 in blue.

Download:

3os3-a2-m1-cA_3os3-a2-m2-cA.pdb.gz

Full biological assembly

Download:

3os3-assembly2.cif.gz