3srk/1/1:B/2:A

Sequences

>3srk-a1-m1-cB (length=405) [Search sequence]

MSQLAHNLTLSIFDPVANYRAARIICTIGPSTQSVEALKGLIQSGMSVARMNFSHGSHEY HQTTINNVRQAAAELGVNIAIALDTKGPEVNLPGCDVDLPAVSAKDRVDLQFGVEQGVDM IFASFIRSAEQVGDVRKALGPKGRDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGV EIPAEKVVVAQKILISKCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCV MLSGETAKGKYPNEVVQYMARICLEAQSALNEYVFFNSIKKLQHIPMSADEAVCSSAVNS VYETKAKAMVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVESVFFDADKL GHDEGKEHRVAAGVEFAKSKGYVQTGDYCVVIHAYANQTRILLVE

>3srk-a1-m2-cA (length=493) [Search sequence]

MSQLAHNLTLSIFDPVANYRAARIICTIGPSTQSVEALKGLIQSGMSVARMNFSHGSHEY HQTTINNVRQAAAELGVNIAIALDTKGPEIRTGQFVGGDAVMERGATCYVTTDPAFADKG TKDKFYIDYQNLSKVVRPGNYIYIDDGILILQVQSHEDEQTLECTVTNSHTISDRRGVNL PGCDVDLPAVSAKDRVDLQFGVEQGVDMIFASFIRSAEQVGDVRKALGPKGRDIMIICKI ENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISKCNVAGKPVICATQML ESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSALNE YVFFNSIKKLQHIPMSADEAVCSSAVNSVYETKAKAMVVLSNTGRSARLVAKYRPNCPIV CVTTRLQTCRQLNITQGVESVFFDADKLGHDEGKEHRVAAGVEFAKSKGYVQTGDYCVVI HAYANQTRILLVE

Structure information

PDB ID	3srk (database links: RCSB PDB PDBe PDBj PDBsum)
Title	A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase
Assembly ID	1
Resolution	2.65Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	63
Sequence identity between the two chains	1.0
PubMed citation

Chain information

	Chain 1	Chain 2
Model ID	1	2
Chain ID	B	A
UniProt accession	Q27686	Q27686
Species	5665 (Leishmania mexicana)	5665 (Leishmania mexicana)
Function annotation	BioLiP:3srkB	BioLiP:3srkA

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 3srk-a1-m1-cB_3srk-a1-m2-cA.pdb.gz

Full biological assembly Download: 3srk-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures	3qv6/1/1:D/2:A 3qv7/1/1:B/1:D 3qv8/1/1:A/2:D
Other dimers with similar sequences but different poses	3qv8/1/2:A/2:D 3qv7/1/1:C/1:B 3qv8/1/1:A/1:D