3ua5/3/2:B/1:A |
| >3ua5-a3-m2-cB (length=462) [Search sequence] |
KLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREAL
VDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQE
EAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSL
ISSVFGQLFELFSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDTY
LLHMEKEKSNAEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQ
VIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFL
ILSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFF
TTILQNFSMASPVAPEDIDLTPQECGVGKIPPTYQIRFLPRH |
| >3ua5-a3-m1-cA (length=465) [Search sequence] |
GKLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREA
LVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQ
EEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFS
LISSVFGQLFELFSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDT
YLLHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYRE
IEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTE
VFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELF
LFFTTILQNFSMASPVAPEDIDLTPQECGVGKIPPTYQIRFLPRH |
|
| PDB ID |
3ua5 (database links:
RCSB PDB
PDBe
PDBj
PDBsum) |
| Title |
Crystal Structure of P450 2B6 (Y226H/K262R) in complex with two molecules of Amlodipine |
| Assembly ID |
3 |
| Resolution |
2.8Å |
| Method of structure determination |
X-RAY DIFFRACTION |
| Number of inter-chain contacts |
30 |
| Sequence identity between the two chains |
1.0 |
| PubMed citation |
22909231 |
|
|
Chain 1 |
Chain 2 |
| Model ID |
2 |
1 |
| Chain ID |
B |
A |
| UniProt accession |
P20813 |
P20813 |
| Species |
9606 (Homo sapiens) |
9606 (Homo sapiens) |
| Function annotation |
BioLiP:3ua5B |
BioLiP:3ua5A |
|
Switch viewer: [NGL] [JSmol]
|
Dimer structure:
Chain 1 in red;
Chain 2 in blue.
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Full biological assembly
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