3uwk/3/2:B/1:A

Sequences
>3uwk-a3-m2-cB (length=196) [Search sequence]
GLFVTLEGPEGAGKSTNRDYLAERLRERGIEVQLTREPGGTPLAERIRELLLAPSDEPMA
ADTELLLMFAARAQHLAGVIRPALARGAVVLCDRFTDATYAYQGGGRGLPEARIAALESF
VQGDLRPDLTLVFDLPVEIGDRFEQEDRRFFEAVRQTYLQRAAQAPERYQVLDAGLPLAE
VQAGLDRLLPNLLERL
>3uwk-a3-m1-cA (length=202) [Search sequence]
GLFVTLEGPEGAGKSTNRDYLAERLRERGIEVQLTREPGGTPLAERIRELLLAPSDEPMA
ADTELLLMFAARAQHLAGVIRPALARGAVVLCDRFTDATYAYQGGGRGLPEARIAALESF
VQGDLRPDLTLVFDLPVEIGLARAAARDRFEQEDRRFFEAVRQTYLQRAAQAPERYQVLD
AGLPLAEVQAGLDRLLPNLLER
Structure information
PDB ID 3uwk (database links: RCSB PDB PDBe PDBj PDBsum)
Title Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation
Assembly ID 3
Resolution 1.91Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 75
Sequence identity between the two chains 0.995
PubMed citation 22243413
Chain information
Chain 1 Chain 2
Model ID 2 1
Chain ID B A
UniProt accession Q9HZN8 Q9HZN8
Species 208964 (Pseudomonas aeruginosa PAO1) 208964 (Pseudomonas aeruginosa PAO1)
Function annotation BioLiP:3uwkB BioLiP:3uwkA
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 3uwk-a3-m2-cB_3uwk-a3-m1-cA.pdb.gz
Full biological assembly
Download: 3uwk-assembly3.cif.gz
Similar dimers
Other dimers with similar sequences and structures 3uwo/3/1:B/1:A 3uxm/5/1:A/2:B 3uxm/6/1:C/1:D 4e5u/1/1:A/1:B 4edh/1/1:A/1:B 4esh/2/1:A/2:A 4gmd/1/1:C/1:A 4gmd/2/1:B/1:D

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