3vw6/1/1:B/1:A

Sequences
>3vw6-a1-m1-cB (length=253) [Search sequence]
LEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPEQPLHEEIALHKHLKHKN
IVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHD
NQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLTGTLQYMAPEIIDKGPRGYGKAADIWS
LGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKR
ACANDLLVDEFLK
>3vw6-a1-m1-cA (length=255) [Search sequence]
LEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPEQPLHEEIALHKHLKHKN
IVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHD
NQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLTFTGTLQYMAPEIIDKGPRGYGKAADI
WSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPD
KRACANDLLVDEFLK
Structure information
PDB ID 3vw6 (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal structure of human apoptosis signal-regulating kinase 1 (ASK1) with imidazopyridine inhibitor
Assembly ID 1
Resolution 2.4Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 26
Sequence identity between the two chains 1.0
PubMed citation 23147077
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID B A
UniProt accession Q99683 Q99683
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:3vw6B BioLiP:3vw6A
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 3vw6-a1-m1-cB_3vw6-a1-m1-cA.pdb.gz
Full biological assembly
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Download: 3vw6-assembly1.cif.gz

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