3vzd/2/1:C/2:A

Sequences

>3vzd-a2-m1-cC (length=346) [Search sequence]

MGSGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVR SEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAG YEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYR RLGEMRFTLGTFLRLAALRTYRGRLAYLPVGRQGPVDAHLVPLEEPVPSHWTVVPDEDFV LVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPY LVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSG

>3vzd-a2-m2-cA (length=349) [Search sequence]

MGSGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVR SEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAG YEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYR RLGEMRFTLGTFLRLAALRTYRGRLAYLPVGRVGSQGPVDAHLVPLEEPVPSHWTVVPDE DFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYE CPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSG

Structure information

PDB ID	3vzd (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal structure of Sphingosine Kinase 1 with inhibitor and ADP
Assembly ID	2
Resolution	2.3Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	29
Sequence identity between the two chains	1.0
PubMed citation	23602659

Chain information

	Chain 1	Chain 2
Model ID	1	2
Chain ID	C	A
UniProt accession	Q9NYA1	Q9NYA1
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:3vzdC	BioLiP:3vzdA

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 3vzd-a2-m1-cC_3vzd-a2-m2-cA.pdb.gz

Full biological assembly Download: 3vzd-assembly2.cif.gz

Similar dimers

Other dimers with similar sequences and structures	3vzd/2/1:B/3:D 3vzd/2/1:B/4:F 3vzd/2/4:F/3:D
Other dimers with similar sequences but different poses	3vzd/1/1:E/1:D 3vzd/1/1:B/1:A 3vzd/2/4:E/4:F 3vzd/1/1:B/1:C 3vzd/1/1:E/1:F 3vzd/2/1:B/1:C 3vzd/2/2:A/3:D 3vzd/1/1:E/1:A 3vzd/1/1:B/1:D