3vzd/2/4:E/4:F |
| >3vzd-a2-m4-cE (length=344) [Search sequence] |
GVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEE
LGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQ
VTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRRLG
EMRFTLGTFLRLAALRTYRGRLAYLPVGRVQGPVDAHLVPLEEPVPSHWTVVPDEDFVLV
LALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLV
YVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSG |
| >3vzd-a2-m4-cF (length=346) [Search sequence] |
MGSGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVR
SEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAG
YEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYR
RLGEMRFTLGTFLRLAALRTYRGRLAYLPVGRQGPVDAHLVPLEEPVPSHWTVVPDEDFV
LVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPY
LVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSG |
|
| PDB ID |
3vzd (database links:
RCSB PDB
PDBe
PDBj
PDBsum) |
| Title |
Crystal structure of Sphingosine Kinase 1 with inhibitor and ADP |
| Assembly ID |
2 |
| Resolution |
2.3Å |
| Method of structure determination |
X-RAY DIFFRACTION |
| Number of inter-chain contacts |
33 |
| Sequence identity between the two chains |
0.997 |
| PubMed citation |
23602659 |
|
|
Chain 1 |
Chain 2 |
| Model ID |
4 |
4 |
| Chain ID |
E |
F |
| UniProt accession |
Q9NYA1 |
Q9NYA1 |
| Species |
9606 (Homo sapiens) |
9606 (Homo sapiens) |
| Function annotation |
BioLiP:3vzdE |
BioLiP:3vzdF |
|
Switch viewer: [NGL] [JSmol]
|
Dimer structure:
Chain 1 in red;
Chain 2 in blue.
|
Full biological assembly
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| Other dimers with similar sequences and structures |
3vzd/1/1:B/1:C 3vzd/1/1:E/1:F 3vzd/2/1:B/1:C 3vzd/2/2:A/3:D |
| Other dimers with similar sequences but different poses |
3vzd/1/1:E/1:D 3vzd/1/1:B/1:A
3vzd/1/1:E/1:A 3vzd/1/1:B/1:D
3vzd/2/1:C/2:A 3vzd/2/1:B/3:D 3vzd/2/1:B/4:F 3vzd/2/4:F/3:D |
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