3w8q/1/1:A/2:A

Sequences
>3w8q-a1-m1-cA (length=318) [Search sequence]
ELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKL
IHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKA
GRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS
MANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQ
RPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRS
DAEEVDFAGWLCSTIGLN
>3w8q-a1-m2-cA (length=318) [Search sequence]
ELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKL
IHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKA
GRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS
MANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQ
RPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRS
DAEEVDFAGWLCSTIGLN
Structure information
PDB ID 3w8q (database links: RCSB PDB PDBe PDBj PDBsum)
Title Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1)
Assembly ID 1
Resolution 2.2Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 136
Sequence identity between the two chains 1.0
PubMed citation 34866601
Chain information
Chain 1 Chain 2
Model ID 1 2
Chain ID A A
UniProt accession Q02750 Q02750
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:3w8qA BioLiP:3w8qA
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 3w8q-a1-m1-cA_3w8q-a1-m2-cA.pdb.gz
Full biological assembly
Download: 3w8q-assembly1.cif.gz

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