3wf8/2/1:A/2:A

Sequences
>3wf8-a2-m1-cA (length=287) [Search sequence]
KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAER
NILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISM
ALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHFCGTIEYMAPEIL
MRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLK
KLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPL
>3wf8-a2-m2-cA (length=287) [Search sequence]
KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAER
NILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISM
ALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHFCGTIEYMAPEIL
MRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLK
KLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPL
Structure information
PDB ID 3wf8 (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal structure of S6K1 kinase domain in complex with a quinoline derivative 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carboxylate
Assembly ID 2
Resolution 1.975Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 63
Sequence identity between the two chains 1.0
PubMed citation 25078151
Chain information
Chain 1 Chain 2
Model ID 1 2
Chain ID A A
UniProt accession P23443 P23443
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:3wf8A BioLiP:3wf8A
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 3wf8-a2-m1-cA_3wf8-a2-m2-cA.pdb.gz
Full biological assembly
Download: 3wf8-assembly2.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 4rlo/3/1:B/1:A 3a60/1/1:B/1:A 4rlp/2/1:A/2:A
    		•

    [Back to Home]