3wig/2/1:A/2:A |
| >3wig-a2-m1-cA (length=278) [Search sequence] |
MELKDDDFEKISELGAGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNS
PYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREK
HKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQ
SDIWSMGLSLVEMAVGRYPIPPPPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCL
IKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIG |
| >3wig-a2-m2-cA (length=278) [Search sequence] |
MELKDDDFEKISELGAGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNS
PYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREK
HKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQ
SDIWSMGLSLVEMAVGRYPIPPPPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCL
IKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIG |
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| PDB ID |
3wig (database links:
RCSB PDB
PDBe
PDBj
PDBsum) |
| Title |
Human MEK1 kinase in complex with CH5126766 and MgAMP-PNP |
| Assembly ID |
2 |
| Resolution |
2.7Å |
| Method of structure determination |
X-RAY DIFFRACTION |
| Number of inter-chain contacts |
70 |
| Sequence identity between the two chains |
1.0 |
| PubMed citation |
24746704 |
|
|
Chain 1 |
Chain 2 |
| Model ID |
1 |
2 |
| Chain ID |
A |
A |
| UniProt accession |
Q02750 |
Q02750 |
| Species |
9606 (Homo sapiens) |
9606 (Homo sapiens) |
| Function annotation |
BioLiP:3wigA |
BioLiP:3wigA |
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Switch viewer: [NGL] [JSmol]
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Dimer structure:
Chain 1 in red;
Chain 2 in blue.
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Full biological assembly
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| Other dimers with similar sequences but different poses |
3dv3/1/1:A/2:A 1s9j/1/1:A/2:A 2p55/1/1:A/2:A 3e8n/2/1:A/2:A 3eqb/1/1:A/2:A 3mbl/1/1:A/2:A 4ark/1/1:A/2:A 4lmn/2/1:A/2:A
5yt3/2/1:C/1:D 5yt3/1/1:A/1:B |
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