4bae/2/1:C/1:D

Sequences

>4bae-a2-m1-cC (length=184) [Search sequence]

GLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGFATRVDVKIHADGSVEVRDDG RGIPVEMHATGMPTIDVVMTQLHGVGVSVVNALSTRLEATVLRDGYEWFQYYDRSVPGKL KQGGETKETGTTIRFWADPEIFETTDYNFETVARRLQEMAFLNKGLTIELTDERDGKHRV FHYP

>4bae-a2-m1-cD (length=185) [Search sequence]

GLEAVRKRPGMYIGSTGERGLHHLIWEVVDNAVDEAMAGFATRVDVKIHADGSVEVRDDG RGIPVEMHATGMPTIDVVMTQLHGVGVSVVNALSTRLEATVLRDGYEWFQYYDRSVPGKL KQGGETKETGTTIRFWADPEIFETTDYNFETVARRLQEMAFLNKGLTIELTDERDGKHRV FHYPG

Structure information

PDB ID	4bae (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Optimisation of pyrroleamides as mycobacterial GyrB ATPase inhibitors: Structure Activity Relationship and in vivo efficacy in the mouse model of tuberculosis
Assembly ID	2
Resolution	2.35Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	47
Sequence identity between the two chains	1.0
PubMed citation	24126580

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	C	D
UniProt accession	P0C559	P0C559
Species	1772 (Mycolicibacterium smegmatis)	1772 (Mycolicibacterium smegmatis)
Function annotation	BioLiP:4baeC	BioLiP:4baeD

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 4bae-a2-m1-cC_4bae-a2-m1-cD.pdb.gz

Full biological assembly Download: 4bae-assembly2.cif.gz

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