4bmm/1/1:B/1:D

Sequences

>4bmm-a1-m1-cB (length=442) [Search sequence]

KLPPVYPVTVPFLGHIVQFGKNPLEFMQRCKRDLKSGVFTISIGGQRVTIVGDPHEHSRF
FSPRNEILSPREVYTIMTPVFGEGVAYAAPYPRMREQLNFLAEELTIAKFQNFVPAIQHE
VRKFMAENWKEDEGVINLLEDCGAMIINTACQCLFGEDLRKRLNARHFAQLLSKMESSLI
PAAVFMPWLLRLPLPQSARCREARAELQKILGEIIVAREKEETSDLLGGLLKAVYRDGTR
MSLHEVCGMIVAAMFAGQHTSTITTSWSMLHLMHPKNKKWLDKLHKEIDEFPAQLNYDNV
MDEMPFAERCVRESIRRDPPLLMVMRMVKAEVKVGSYVVPKGDIIACSPLLSHHDEEAFP
NPRLWDPERDEKVDGAFIGFGAGVHKCIGQKFALLQVKTILATAFREYDFQLLRDEVPDP
DYHTMVVGPTLNQCLVKYTRKK

>4bmm-a1-m1-cD (length=442) [Search sequence]

KLPPVYPVTVPFLGHIVQFGKNPLEFMQRCKRDLKSGVFTISIGGQRVTIVGDPHEHSRF
FSPRNEILSPREVYTIMTPVFGEGVAYAAPYPRMREQLNFLAEELTIAKFQNFVPAIQHE
VRKFMAENWKEDEGVINLLEDCGAMIINTACQCLFGEDLRKRLNARHFAQLLSKMESSLI
PAAVFMPWLLRLPLPQSARCREARAELQKILGEIIVAREKEEASDLLGGLLKAVYRDGTR
MSLHEVCGMIVAAMFAGQHTSTITTSWSMLHLMHPKNKKWLDKLHKEIDEFPAQLNYDNV
MDEMPFAERCVRESIRRDPPLLMVMRMVKAEVKVGSYVVPKGDIIACSPLLSHHDEEAFP
NPRLWDPERDEKVDGAFIGFGAGVHKCIGQKFALLQVKTILATAFREYDFQLLRDEVPDP
DYHTMVVGPTLNQCLVKYTRKK

Structure information

PDB ID	4bmm (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-2',3, 5'-trifluoro-(1,1'-biphenyl)-4-carboxamide
Assembly ID	1
Resolution	2.84Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	72
Sequence identity between the two chains	0.998
PubMed citation	25101801

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	B	D
UniProt accession	Q7Z1V1	Q7Z1V1
Species	353153 (Trypanosoma cruzi strain CL Brener)	353153 (Trypanosoma cruzi strain CL Brener)
Function annotation	BioLiP:4bmmB	BioLiP:4bmmD

3D structure

Switch viewer: [NGL] [JSmol]

Dimer structure: Chain 1 in red; Chain 2 in blue.

Download:

4bmm-a1-m1-cB_4bmm-a1-m1-cD.pdb.gz

Full biological assembly

Download:

4bmm-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures	2wuz/1/1:A/1:B 4bmm/2/1:C/1:A
Other dimers with similar sequences but different poses	4c0c/1/2:A/3:A 4c0c/1/1:A/2:A 4c0c/1/1:A/3:A 4uqh/1/1:A/2:A 4uqh/1/1:A/3:A 4uqh/1/2:A/3:A