4cku/2/1:E/1:B

Sequences
>4cku-a2-m1-cE (length=322) [Search sequence]
SNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSS
KSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFD
GILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGP
LTYEKLNHDLYWQITLDAHVGNISLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVPF
LPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHGLCMLNIIGLDFPVPTFILGDPFMR
KYFTVFDYDNHSVGIALAKKNL
>4cku-a2-m1-cB (length=327) [Search sequence]
NDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSK
SRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDG
ILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEGPL
TYEKLNHDLYWQITLDAHVGNISLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVPFL
PFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVPTFILG
DPFMRKYFTVFDYDNHSVGIALAKKNL
Structure information
PDB ID 4cku (database links: RCSB PDB PDBe PDBj PDBsum)
Title Three dimensional structure of plasmepsin II in complex with hydroxyethylamine-based inhibitor
Assembly ID 2
Resolution 1.85Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 15
Sequence identity between the two chains 0.997
PubMed citation 24900843
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID E B
UniProt accession P46925 P46925
Species 5833 (Plasmodium falciparum) 5833 (Plasmodium falciparum)
Function annotation BioLiP:4ckuE BioLiP:4ckuB
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 4cku-a2-m1-cE_4cku-a2-m1-cB.pdb.gz
Full biological assembly
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Download: 4cku-assembly2.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 1lee/3/3:A/4:A 1lee/2/1:A/2:A 1lee/3/1:A/2:A
  • 4cku/1/2:A/2:F 1lee/3/1:A/3:A 1lee/3/2:A/4:A 4cku/1/1:A/1:F 4cku/2/1:C/1:B 4cku/2/1:E/1:D
  • 3f9q/1/1:A/2:A 1lf3/2/1:A/2:A 2igx/2/1:A/2:A
  • 1xdh/1/1:A/1:B 1m43/3/1:A/1:B 1me6/3/1:A/2:B 1w6i/3/1:A/2:C 1xe5/1/1:A/1:B 1xe6/1/1:A/1:B
  • 1pfz/6/1:C/1:A 1pfz/5/1:D/1:B
  • 4cku/1/1:A/2:F 4cku/1/2:A/1:F 4cku/2/1:C/1:E 4cku/2/1:D/1:B
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