4cl1/1/1:A/1:B

Sequences
>4cl1-a1-m1-cA (length=155) [Search sequence]
PFVSCQRGYRGVWRGDGIMHTRCHCGAEITGHVKNGTMRIVGPRTCRNMWSGTFPINAYT
TGPCTPLPAPNYKFALWRVSAEEYVEIRRVGDFHYVSGMTTDNLKCPCQIPSPEFFTELD
GVRLHRFAPPCKPLLREVSFRVHEYPVGSQLPCEP
>4cl1-a1-m1-cB (length=157) [Search sequence]
PFVSCQRGYRGVWRGDGIMHTRCHCGAEITGHVKNGTMRIVGPRTCRNMWSGTFPINAYT
TGPCTPLPAPNYKFALWRVSAEEYVEIRRVGDFHYVSGMTTDNLKCPCQIPSPEFFTELD
GVRLHRFAPPCKPLLREEVSFRVGLHEYPVGSQLPCE
Structure information
PDB ID 4cl1 (database links: RCSB PDB PDBe PDBj PDBsum)
Title The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors
Assembly ID 1
Resolution 3.5Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 25
Sequence identity between the two chains 0.994
PubMed citation 24639329
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID A B
UniProt accession K4KA16 K4KA16
Species 63746 (Hepatitis C virus (isolate H77)) 63746 (Hepatitis C virus (isolate H77))
Function annotation BioLiP:4cl1A BioLiP:4cl1B
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Color: [By chain]   [By residue index]  
Spin: [Spin off]   [Spin on]   [Reset]
Render: [Low quality]   [High quality]  
Background: [Black]   [White]  
Download: 4cl1-a1-m1-cA_4cl1-a1-m1-cB.pdb.gz
Full biological assembly
Color: [By chain]   [By residue index]  
Spin: [Spin off]   [Spin on]   [Reset]
Render: [Low quality]   [High quality]  
Background: [Black quality]   [White quality]  
Download: 4cl1-assembly1.cif.gz

[Back to Home]