4cl1/1/1:C/1:D

Sequences
>4cl1-a1-m1-cC (length=157) [Search sequence]
FVSCQRGYRGVWRGDGIMHTRCHCGAEITGHVKNGTMRIVGPRTCRNMWSGTFPINAYTT
GPCTPLPAPNYKFALWRVSAEEYVEIRRVGDFHYVSGMTTDNLKCPCQIPSPEFFTELDG
VRLHRFAPPCKPLLREEVSFRVGLHEYPVGSQLPCEP
>4cl1-a1-m1-cD (length=160) [Search sequence]
PFVSCQRGYRGVWRGDGIMHTRCHCGAEITGHVKNGTMRIVGPRTCRNMWSGTFPINAYT
TGPCTPLPAPNYKFALWRVSAEEYVEIRRVGDFHYVSGMTTDNLKCPCQIPSPEFFTELD
GVRLHRFAPPCKPLLREEVSFRVGLHEYPVGSQLPCEPEP
Structure information
PDB ID 4cl1 (database links: RCSB PDB PDBe PDBj PDBsum)
Title The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors
Assembly ID 1
Resolution 3.5Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 24
Sequence identity between the two chains 1.0
PubMed citation 24639329
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID C D
UniProt accession K4KA16 K4KA16
Species 63746 (Hepatitis C virus (isolate H77)) 63746 (Hepatitis C virus (isolate H77))
Function annotation BioLiP:4cl1C BioLiP:4cl1D
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 4cl1-a1-m1-cC_4cl1-a1-m1-cD.pdb.gz
Full biological assembly
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Download: 4cl1-assembly1.cif.gz

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