4fzb/4/1:N/1:P

Sequences
>4fzb-a4-m1-cN (length=177) [Search sequence]
GSAKLISVTKPVVEGVNTAEELIAYAARVSTASGLLKYCIRHKHWSIFETAFMTLELKTS
RGIAAQVLRHRSFHFQEFSQRYAQTWWATEQEKLYAQSMELYNKALEKGIAKECARFILP
LSTPTTIYMSGTIRDWIHYIELRTSNGTQREHIDLANACKEIFIKEFPSIAKALDWV
>4fzb-a4-m1-cP (length=197) [Search sequence]
GSAKLISVTKPVVEGVNTAEELIAYAARVSNPENQINNKTASGLLKYCIRHKHWSIFETA
FMTLELKTSRGIAAQVLRHRSFHFQEFSQRYASVMETPPPHQDDQTWWATEQEKLYAQSM
ELYNKALEKGIAKECARFILPLSTPTTIYMSGTIRDWIHYIELRTSNGTQREHIDLANAC
KEIFIKEFPSIAKALDW
Structure information
PDB ID 4fzb (database links: RCSB PDB PDBe PDBj PDBsum)
Title Structure of thymidylate synthase ThyX complexed to a new inhibitor
Assembly ID 4
Resolution 2.59Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 94
Sequence identity between the two chains 0.994
PubMed citation 23155486
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID N P
UniProt accession O41156 O41156
Species 10506 (Paramecium bursaria Chlorella virus 1) 10506 (Paramecium bursaria Chlorella virus 1)
Function annotation BioLiP:4fzbN BioLiP:4fzbP
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 4fzb-a4-m1-cN_4fzb-a4-m1-cP.pdb.gz
Full biological assembly
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Download: 4fzb-assembly4.cif.gz
Similar dimers
Other dimers with similar sequences and structures 4fzb/1/1:A/1:C 4fzb/1/1:B/1:D 4fzb/2/1:G/1:E 4fzb/2/1:H/1:F 4fzb/3/1:I/1:K 4fzb/3/1:J/1:L 4fzb/4/1:M/1:O
Other dimers with similar sequences but different poses
  • 4fzb/1/1:D/1:C 4fzb/1/1:B/1:A 4fzb/2/1:E/1:F 4fzb/2/1:H/1:G 4fzb/3/1:J/1:I 4fzb/3/1:K/1:L 4fzb/4/1:N/1:M 4fzb/4/1:P/1:O
    		•

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