4i5i/3/1:A/1:B

Sequences

>4i5i-a3-m1-cA (length=272) [Search sequence]

NTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIE
YFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRII
QCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPE
QFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLG
DCDVIINELCHRLGGEYAKLCCNPVKLSEITE

>4i5i-a3-m1-cB (length=272) [Search sequence]

Structure information

PDB ID	4i5i (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal structure of the SIRT1 catalytic domain bound to NAD and an EX527 analog
Assembly ID	3
Resolution	2.5Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	62
Sequence identity between the two chains	1.0
PubMed citation	23311358

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	A	B
UniProt accession	Q96EB6	Q96EB6
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:4i5iA	BioLiP:4i5iB

3D structure

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Dimer structure: Chain 1 in red; Chain 2 in blue.

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Download:	4i5i-a3-m1-cA_4i5i-a3-m1-cB.pdb.gz

Full biological assembly

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Download:	4i5i-assembly3.cif.gz