4l7d/1/1:B/1:C |
| >4l7d-a1-m1-cB (length=285) [Search sequence] |
RLIYTAGGYFRQSLSYLEAYNPSDGTWLDLADLQVPRSGLAGCVVGGLLYAVGGRNNSPD
GNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEP
ERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNT
IRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGR
IYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTL |
| >4l7d-a1-m1-cC (length=287) [Search sequence] |
GRLIYTAGGYFRQSLSYLEAYNPSDGTWLDLADLQVPRSGLAGCVVGGLLYAVGGRNNSP
DGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYE
PERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMN
TIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQG
RIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTLE |
|
| PDB ID |
4l7d (database links:
RCSB PDB
PDBe
PDBj
PDBsum) |
| Title |
Structure of keap1 kelch domain with (1S,2R)-2-{[(1S)-5-methyl-1-[(1-oxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}cyclohexanecarboxylic acid |
| Assembly ID |
1 |
| Resolution |
2.25Å |
| Method of structure determination |
X-RAY DIFFRACTION |
| Number of inter-chain contacts |
57 |
| Sequence identity between the two chains |
1.0 |
| PubMed citation |
24504667 |
|
|
Chain 1 |
Chain 2 |
| Model ID |
1 |
1 |
| Chain ID |
B |
C |
| UniProt accession |
Q14145 |
Q14145 |
| Species |
9606 (Homo sapiens) |
9606 (Homo sapiens) |
| Function annotation |
BioLiP:4l7dB |
BioLiP:4l7dC |
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Switch viewer: [NGL] [JSmol]
|
Dimer structure:
Chain 1 in red;
Chain 2 in blue.
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Full biological assembly
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| Other dimers with similar sequences and structures |
4l7c/1/1:B/1:C 4n1b/1/1:B/1:C 7k2b/1/1:B/1:A |
| Other dimers with similar sequences but different poses |
3zgd/1/1:A/1:B 4l7b/1/1:A/1:B 6fmp/1/1:A/1:B 6fmq/1/1:A/1:B 6rog/1/1:A/1:X |
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