4mpc/1/1:A/2:A

Sequences

>4mpc-a1-m1-cA (length=363) [Search sequence]

SLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINLL
PDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMA
QGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDPAHPKHIGSIDPNC
NVSEVVKDAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKN
AMRATVESHESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTGYGLP
ISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDW
CVP

>4mpc-a1-m2-cA (length=363) [Search sequence]

Structure information

PDB ID	4mpc (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS2
Assembly ID	1
Resolution	1.699Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	158
Sequence identity between the two chains	1.0
PubMed citation	24356970

Chain information

	Chain 1	Chain 2
Model ID	1	2
Chain ID	A	A
UniProt accession	Q15119	Q15119
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:4mpcA	BioLiP:4mpcA

3D structure

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Dimer structure: Chain 1 in red; Chain 2 in blue.

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Download:	4mpc-a1-m1-cA_4mpc-a1-m2-cA.pdb.gz

Full biological assembly

Download:

4mpc-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures

2bu2/1/1:A/2:A 2bu8/1/1:A/2:A 3crl/1/1:A/1:B 4mp2/1/1:A/2:A 4mp7/1/1:A/2:A 4mpe/1/1:A/2:A 4mpn/1/1:A/2:A 4v25/1/1:A/2:A 4v26/1/1:A/2:A 5j6a/1/1:A/2:A 6lil/1/1:B/1:A 6lin/1/1:B/1:A 6lin/2/1:D/1:C 6lio/1/1:A/1:B 7eas/1/1:A/2:A 7ebh/1/1:A/2:A 7vbx/1/1:A/2:A