4nct/5/1:D/1:A

Sequences
>4nct-a5-m1-cD (length=331) [Search sequence]
KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNK
KAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTN
FRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQ
LGQRIYQIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIV
EVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKYKPPGTRKLHNILGVETGGPGGTVADY
LKFKDLILRMLDYDPKTRIQPYYALQHSFFK
>4nct-a5-m1-cA (length=341) [Search sequence]
KVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNK
KAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTN
FRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQ
LGQRIYQIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIV
EVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTEYKPPGTRKLHNILGVETGGPGGRRA
GESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK
Structure information
PDB ID 4nct (database links: RCSB PDB PDBe PDBj PDBsum)
Title Human DYRK1A in complex with PKC412
Assembly ID 5
Resolution 2.597Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 42
Sequence identity between the two chains 1.0
PubMed citation 25945585
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID D A
UniProt accession Q13627 Q13627
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:4nctD BioLiP:4nctA
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 4nct-a5-m1-cD_4nct-a5-m1-cA.pdb.gz
Full biological assembly
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Download: 4nct-assembly5.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 4nct/5/1:D/1:C 4nct/5/1:B/1:A
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