4o0t/3/1:B/1:A

Sequences
>4o0t-a3-m1-cB (length=280) [Search sequence]
EKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIIN
EILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECL
QALEFLHSNQVIHRNIKSDNILLGMDGSVKLTDFEQSKRSEMVGTPYWMAPEVVTRKAYG
PKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCL
EMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATK
>4o0t-a3-m1-cA (length=292) [Search sequence]
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKE
LIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVC
RECLQALEFLHSNQVIHRNIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSEMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKL
SAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATK
Structure information
PDB ID 4o0t (database links: RCSB PDB PDBe PDBj PDBsum)
Title Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors
Assembly ID 3
Resolution 2.6Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 51
Sequence identity between the two chains 1.0
PubMed citation 24432870
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID B A
UniProt accession Q13153 Q13153
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:4o0tA
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 4o0t-a3-m1-cB_4o0t-a3-m1-cA.pdb.gz
Full biological assembly
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Download: 4o0t-assembly3.cif.gz

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