4o67/1/1:A/1:B

Sequences
>4o67-a1-m1-cA (length=346) [Search sequence]
GASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTKISAPNEFD
VMFKLEVPRIQLEEYSNTRAYYFVKFKRNKENPLSQFLEGEILSASKMLSKFRKIIKEEI
NDIKDTDVIMKRKRGGSPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKV
RKQLRLKPFYLVPKHAEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKY
LLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCL
RTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFDE
>4o67-a1-m1-cB (length=347) [Search sequence]
GASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNVKISAPNEFD
VMFKLEVPRIQLEEYSNTRAYYFVKFKRNKENPLSQFLEGEILSASKMLSKFRKIIKEEI
NDIKDTDVIMKRKRGGSPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKV
RKQLRLKPFYLVPKHAQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMK
YLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQC
LRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFDE
Structure information
PDB ID 4o67 (database links: RCSB PDB PDBe PDBj PDBsum)
Title Human cyclic GMP-AMP synthase (cGAS) in complex with GAMP
Assembly ID 1
Resolution 2.444Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 20
Sequence identity between the two chains 0.997
PubMed citation 24462292
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID A B
UniProt accession Q8N884 Q8N884
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:4o67A BioLiP:4o67B
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 4o67-a1-m1-cA_4o67-a1-m1-cB.pdb.gz
Full biological assembly
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Download: 4o67-assembly1.cif.gz

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