4oav/1/1:B/1:D

Sequences
>4oav-a1-m1-cB (length=673) [Search sequence]
EDNHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGA
DPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKF
LYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGR
NALIHALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEH
IEINDTDSDGKTALLLAVELKLKKIAELLCKRGASTDCGDLVMTARRNYDHSLVKVLLSH
GAKEWKPQSSHWGAALKDLHRIYRPMIGKLKFFIDEKYKIADTSEGGIYLGFYEKQEVAV
KTFCEGSPRAQREVSCLQSSRENSHLVTFYGSESHRGHLFVCVTLCEQTLEACLDVEEDE
FARNVLSSIFKAVQELHLSCGYTHQDLQPQNILIDSKKAAHLADFDKSIKWAGDPQEVKR
DLEDLGRLVLYVVKKGSISFEDLKAQSNEEVVQLSPDEETKDLIHRLFHPGEHVRDCLSD
LLGHPFFWTWESRYRTLRNVGNESDIKTRKSESEILRLLQPGPSEHSKSFDKWTTKINEC
VMKKMNKFYEKRGNFYQNTVGDLLKFIRNLGENIDKMKLKIGDPSLYFQKTFPDLVIYVY
TKLQNTEYRKHFP
>4oav-a1-m1-cD (length=674) [Search sequence]
NHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADP
VLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLY
KRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNA
LIHALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIE
INDTDSDGKTALLLAVELKLKKIAELLCKRGASTDCGDLVMTARRNYDHSLVKVLLSHGA
KEWKPQSSHWGAALKDLHRIYRPMIGKLKFFIDEKYKIADTSEGGIYLGFYEKQEVAVKT
FCEGSPRAQREVSCLQSSRENSHLVTFYGSESHRGHLFVCVTLCEQTLEACLDVNEEDEF
ARNVLSSIFKAVQELHLSCGYTHQDLQPQNILIDSKKAAHLADFDKSIKWAGDPQEVKRD
LEDLGRLVLYVVKKGSISFEDLKAQSNEEVVQLSPDEETKDLIHRLFHPGEHVRDCLSDL
LGHPFFWTWESRYRTLRNVGNESDIKTRKSESEILRLLQPGPSEHSKSFDKWTTKINECV
MKKMNKFYEKRGNFYQNTVGDLLKFIRNLGENIDEMKLKIGDPSLYFQKTFPDLVIYVYT
KLQNTEYRKHFPQT
Structure information
PDB ID 4oav (database links: RCSB PDB PDBe PDBj PDBsum)
Title Complete human RNase L in complex with 2-5A (5'-ppp heptamer), AMPPCP and RNA substrate.
Assembly ID 1
Resolution 2.1Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 133
Sequence identity between the two chains 0.996
PubMed citation 24578532
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID B D
UniProt accession Q05823 Q05823
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:4oavB BioLiP:4oavD
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 4oav-a1-m1-cB_4oav-a1-m1-cD.pdb.gz
Full biological assembly
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Download: 4oav-assembly1.cif.gz
Similar dimers

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