4pgz/1/1:C/2:C

Sequences
>4pgz-a1-m1-cC (length=165) [Search sequence]
DKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSENE
SNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILIRMLQCVAAGFP
EPTIDWYFCVQTLNSSGPPFGKLVVQSSICKAYNDVGKTSAYFNF
>4pgz-a1-m2-cC (length=165) [Search sequence]
DKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSENE
SNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILIRMLQCVAAGFP
EPTIDWYFCVQTLNSSGPPFGKLVVQSSICKAYNDVGKTSAYFNF
Structure information
PDB ID 4pgz (database links: RCSB PDB PDBe PDBj PDBsum)
Title Structural basis of KIT activation by oncogenic mutations in the extracellular region reveals a zipper-like mechanism for ligand-dependent or oncogenic receptor tyrosine kinase activation
Assembly ID 1
Resolution 2.4Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 43
Sequence identity between the two chains 1.0
Chain information
Chain 1 Chain 2
Model ID 1 2
Chain ID C C
UniProt accession P10721 P10721
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 4pgz-a1-m1-cC_4pgz-a1-m2-cC.pdb.gz
Full biological assembly
Download: 4pgz-assembly1.cif.gz

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